Arizona Cardinals vs. Cincinnati Bengals Picks and Prediction for Sunday, December 28th, 2025
Use Code WWWC The Arizona Cardinals (3-12, 6-9 ATS, 9-6 O/U) meet the Cincinnati Bengals (5-10, 7-8 ATS, 8-6-1 O/U) in an AFC clash on Sunday afternoon, and we have the prediction. The Cardinals were hit with a home loss by the Falcons in their previous action. The Bengals posted a road win against the Dolphins last week.
Can the Bengals post their sixth win of the season on Sunday? Check out the Cardinals vs. Bengals prediction. Do you need a boost in your handicapping? Try our NFL Betting Picks!
Arizona Tagged with 12th Defeat of Season
The Arizona Cardinals are seeking confidence before the season wraps up. Arizona is having a disappointing season. They were 2-0 to begin the year and have managed just one win since. Arizona was dealt a home loss by the Rams earlier this month and a 40-20 road defeat by the Texans two weeks ago. Next, Arizona dropped a 26-19 home decision against the Falcons last week in a game that had the Cardinals marked as 2.5-point dogs. The Cardinals have covered the spread in two of their past five games.
Kyler Murray has only played five games and is out for the rest of the year. Jacoby Brissett will be under center. The 33-year-old QB has been sharp, posting at least 250 yards in all but two games. Brissett has posted 2911 passing yards and a 19:7 TD to INT ratio. Arizona has a supbar running game.
Get Free $30 Credit for Premium Picks + Exclusive Discounts
Subscribe Now
Michael Carter has posted 65 yards last week and has picked up 286 rushing yards. Emari Demercado has 272 yards in 11 games. The receiving core is a strength. Trey McBride is one of the best tight ends in the game. The 26-year-old has reached 100 yards in three games and has netted 1098 receiving yards on the season. The Arizona offense recorded 320 yards last week. They are averaging 332 yards per game.
The Cardinals' defense is a weakness. The unit has squandered 35 or more points in five of its past six games. Buddy Baker has been a positive force, making 111 combined tackles. He is questionable with a concussion. The Cardinals squandered 342 total yards last week, dipping their season average to 350 yards per game. The pass defense is marked 21st while the rush defense is 23rd.
Arizona is averaging 21.4 points on the season, ranking them 20th. The Cardinals are conceding an average of 27.6 points, pegging them 29th in the NFL.
Bengals Target Sixth Win of Season
The Cincinnati Bengals are targeting their sixth win of the season. Cincinnati had big expectations entering the season, but the injury to Joe Burrow put a damper on the season. The Bengals have won just two of their past five games. This includes a road win against the Ravens to begin the month. Cincinnati sustained a home loss to the Ravens in the rematch a few weeks ago. The Bengals answered with a 45-21 road win against the Dolphins on Sunday. They were 3.5-point favorites in that one. The Bengals have covered the spread in four of their past five games.
Joe Burrow has been a huge threat since his return from injury. The 29-year-old star QB has amassed more than 260 passing yards in three of his past four games. He posted 309 yards in the win last week and has recorded 1268 passing yards and a 12:4 TD to INT ratio on the season. The rushing offense is a weakness. Chase Brown has been decent, netting at least 50 yards in five of his last six games. Brown has amassed 846 rushing yards on the season.
The receiving group is strong. Ja’Marr Chase has been a beast, surpassing 100 yards in five of his past eight games. Chase had 109 yards last week and has registered 1256 receiving yards on the season. Tee Higgins is next with 720 receiving yards. The Cincinnati offense delivered 407 total yards in the win last week. This improves its season average to 320 yards per game.
The Bengals' defense has been a disaster most of the season. The unit ranks near the bottom in most categories. The defense has been better this month, conceding 26 or fewer points in four of their past five games. They gave up 390 yards last week, and are squandering an average of 402 yards per game on the season. DJ Turner II has been steady in the secondary, breaking up 17 passes. The pass defense is marked 29th, while the rush defense has been exposed and stands 32nd.
Cincinnati is scoring an average of 23.9 points on the season, ranking them 15th. The Bengals are conceding an average of 30.5 points, placing them 32nd in the NFL.
Cardinals vs. Bengals Pick
Spread Pick for Cardinals vs. Bengals
- Cincinnati Bengals -7.5 (5 units)
The Arizona Cardinals have been a disaster in the late stages of this season and have dropped six straight games. This is a team that was 2-0 and has managed just one win since. Arizona stands at 1-5 in its past six road games. The Cincinnati Bengals have been a lot better since the return of Joe Burrow last month. They beat the Dolphins by a 45-21 score last week. Cincinnati is sporting a 3-2 record with Joe Burrow under center.
Furthermore, the Cardinals' defense has been exposed. The pass defense is ranked 21st in the NFL. Joe Burrow had 309 passing yards last week and should expose their weak secondary. Also, Arizona is not scoring enough points to stay in games. They have only averaged 19 points in their last five games. The Bengals' defense has displayed some improvement late this season, conceding a total of 45 points in their past two games. The Bengals' past two wins have been by more than 20 points.
Over/Under Pick for Cardinals vs. Bengals
- Over 52.5 (5 units)
I expect plenty of scoring in this one. Arizona has a potent passing offense with Jacob Brissett. They are averaging 235 passing yards per game, rating them ninth. Arizona will have a big output in the air against a weak Bengals' pass defense, which is ranked 28th in the NFL.
In addition, Cincinnati has averaged 26.2 points in its past five games, including 32 against the Ravens and 45 points in the win last week. The Cardinals' defense has not been able to contain the opposition, surrendering an average of 33 points in their past five games. The over is a convincing 7-3 in the Cardinals' past 10 games.
Betting on the NFL?
- Be sure to look our our list of the best NFL online sportsbooks
- Grow your bankroll by claiming one of our favorite NFL sportsbook promo codes
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days
