Carolina Panthers at Green Bay Packers, Preview, Odds, Picks and Prediction, Sunday, November 2nd, 2025

In this Panthers at Packers prediction, the Panthers travel to Wisconsin to battle the Packers in an NFC showdown. The Panthers had their three-game winning streak snapped last week and come into this game with a 4-4 record. The Packers have been one of the top teams in the NFC this season, coming in with a record of 5-1-1. The opening kick is scheduled for 1:00 pm EST. If you need quality winners, this is the ultimate site for NFL Picks.

Carolina Looks to Start New Streak

The Carolina Panthers’ three-game winning streak came crashing down at home last week in a 40-9 loss to the visiting Buffalo Bills. Andy Dalton got the start in place of injured QB Bryce Young, and things never got untracked. Dalton contributed to three turnovers, fumbling twice and throwing an interception in the blowout loss.

“It’s tough," Dalton said. “Obviously I’ve got to do a better job of protecting the ball, especially at that point early in the game when we had some momentum. We were close to scoring and I’ve got to hold on to it.”

Dalton finished the game 16-of-24 for 175 yards and the interception. The Bills fell behind early and were never able to establish the team’s ground game. RB Rico Dowdle finished the game with 54 yards rushing on just eight carries, while teammate Chuba Hubbard ran for 34 yards on 12 carries with a touchdown. Wide receiver Tetairoa McMillan finished the game with seven catches for 99 yards. In all, the Panthers had 244 yards of total offense.

The Panthers’ defense never stood a chance in a game featuring three turnovers from their offense. They allowed 410 yards of total offense to the Bills, including a whopping 245 yards on the ground. Linebacker Christian Rozeboom led the team with 12 tackles, including two tackles for loss. Trevin Wallace had seven tackles and a sack in the contest. The defense did not force any turnovers in the game.

The Panthers come into this game ranked just 27th in the NFL in points per game. They are 10th in rushing and 29th in passing. The Panthers are 17th in red zone offense and are 17th in sacks allowed per game. On the defensive end, the Panthers are ranked 20th in points allowed per game. They are ranked 24th against the run and 10th against the pass. The Panthers’ defense ranks 13th in the red zone. They are 27th in sacks per game and 7th in penalty yards per game. The Panthers are just 26th in turnover margin in the NFL.

Key Injuries: LB Trevin Wallace, LB Princely Umanmielen, S Nick Scott, and QB Andy Dalton are questionable. G Chandler Zavala is out.

Packers Ahead of the Pack

The Green Bay Packers return home after a successful trip to Pittsburgh on Sunday night. The Pack took out the Steelers 35-25, outscoring them 28-9 in the second half. They have now won two straight games and stand alone in the NFC North at 5-1-1. Quarterback Jordan Love outdueled his mentor, Aaron Rodgers, throwing for three touchdowns to lead the dominant Packers’ attack.

“My mindset was just trying to come out here and focus on getting that win, trying to block all that extra stuff out and just be the player I need to be," Love said.

Love finished the game with 360 yards passing to go along with the three touchdown passes. He completed 29-of-35 passes, including a franchise-record-tying 20 straight completions. Tight end Tucker Kraft benefitted from Love’s accuracy, hauling in seven passes for a career-high 143 yards and two touchdowns. Wide receiver Christian Watson, returning from a torn ACL at the end of last season, had four catches for 85 yards in the win. The Packers finished with 454 yards of total offense.

After giving up 16 points in the first half, the Packers’ defense settled in, allowing just nine points in the second half. The Packers' defensive line pressured Rodgers in the second half, finishing with three sacks, two by Rashan Gary and one by Micah Parsons. Xavier McKinney led the team with seven tackles. In all, the Packers held the Steelers to 295 yards of total offense. They were particularly tough on third down, limiting the Steelers to 1-of-10 on third down conversions.

The Packers are ranked fifth in the NFL in scoring this season. They are 24th in rushing and 7th in passing. The Pack ranks second in the NFL in red zone offense. They are fifth in sacks allowed per game. Defensively, the Packers are 10th in points allowed per game. They are fourth against the run and 15th against the pass. The Packers are 21st in red zone defense and eighth in sacks per game. The team is 24th in penalty yards per game and 14th in turnover margin.

Key Injuries: K Brandon McManus, WR Christian Watson, WR Dontayvion Wicks, and RB Josh Jacobs are questionable. WR Jayden Reed is out.

Panthers vs. Packers Pick

Point Spread Pick for Panthers at Packers 

• Packers -13.5 (4 units)

The line has jumped two points since opening at 11.5, and for good reason. The Packers’ stout defense will cause major problems for a Panthers team that is below average at protecting the quarterback. The Packers' offense received a boost with the return of Watson. He gives Love a deep threat and forces the Panthers to keep their safeties back. Running back Jacobs should have a big day as well, against the NFL’s 24th-ranked rushing defense. The Panthers fell behind early against Buffalo and were never able to unleash their best weapon, their ground game. Expect similar results here, with the Packers jumping on top and forcing the Panthers' offense to be one-dimensional. That will expose Young and shift this game heavily in Green Bay’s favor.

Take the Packers -13.5

Over/Under Pick for Panthers at Packers 

• Over 44.5 (4 units)

The total has gone up two points as well, after opening at 42.5. That total should easily be reached in this game. The Panthers have allowed over 40 points per game in each of their last two losses. They have also gone over this number in four of their last five games. The Packers are averaging over 32 points per game in their last four. They are fifth in the NFL in points per game this year. This one should be a layup, take the over.

Take the over, 44.5