Carolina Panthers vs. New Orleans Saints, Picks and Prediction, Sunday, December 14, 2025
Use Code WWWC Carolina (7-6) will be trying to increase their lead in the NFC South when they visit Caesars Superdome on Sunday afternoon to face New Orleans (3-10) at 4:25 PM. ET. Read on to find out which team picks up the win in this Panthers vs. Saints prediction. Looking to win big this football season? We have the best NFL Picks to help you out!
The Panthers are coming off a 31-28 win over the Rams as 10-point underdogs. The Saints are coming off a 24-20 win over Tampa Bay as 7.5-point underdogs.
New Orleans is 6-4 in its last 10 games against Carolina. The Saints won the first meeting of the season, 17-7.
Panthers Going For Second Consecutive Win
The Panthers bounced back from their loss to the 49ers with a surprising win over the heavily favored Rams in their last game. With Tampa Bay losing to Atlanta on Thursday night, they are on top of the NFC South. They bounced back after a 20-9 loss to the 49ers in the previous game and have not won two or more straight games since mid-October.
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Carolina averages 19 points per game, which is 28th in the league. They throw for 185.7 yards and rush for 125.5 yards per game.
Bryce Young has completed 63.4 percent of his passes for 2,337 yards, 18 touchdowns, and nine interceptions. Rico Dowdle leads the team with 192 carries for 929 yards and five touchdowns, while Tetairoa McMillan has 57 catches for 826 yards and six touchdowns.
Carolina is giving up 22.8 points per game, which is 16th in the league. They’re giving up 212.4 passing yards and 118.7 rushing yards per game.
Key Injuries for Panthers
- CB Jaycee Horn (concussion) is questionable.
Saints Going For Series Sweep
The Saints snapped their two-game losing streak with a win over the Buccaneers in their last game. They won the first meeting between the two teams and will try to get the sweep with a win on Sunday.
New Orleans averages 15.8 points per game, which is 30th in the league. They throw for 199.4 yards and rush for 94.4 yards per game.
Rookie QB Tyler Shough has completed 65.2 percent of his passes for 1,212 yards, five touchdowns, and five interceptions. Alvin Kamara leads the team with 131 carries for 471 yards and one touchdown, while Chris Olave leads the team with 76 catches for 811 yards and five touchdowns. Kamara will miss this game due to a knee injury.
New Orleans is giving up 24.2 points per game, which is 20th in the league. They’re giving up 182.6 passing yards and 130.9 rushing yards per game.
Key Injuries for Saints:
- RB Alvin Kamara (knee) is out. Leading rusher.
- S JUstin Reid (knee) is questionable.
- OT Asim Richards is out.
Panthers vs. Saints Picks
Point Spread Pick for Panthers vs. Saints
- Carolina Panthers -2.5 (4 Units)
The Panthers have won two of their last three games, while the Saints have lost two of their last three games. Carolina has the edge here because they’re playing well offensively and scored more than 30 points in two of their last three games. They’ve been able to move the ball effectively on the ground, and they’re facing a team that has been unable to stop the run, especially in recent weeks, so expect them to pound the ball on the ground in this game.
The Saints will have a hard time keeping up offensively because they don’t have a running game and rely heavily on their pass game. With the Panthers not having to worry about the Saints beating them through the air, expect them to keep pressure on Shough and force him to make costly mistakes. Take Carolina to cover the spread.
Over/Under Pick for Panthers vs. Saints
- Over 40.5 (4 units)
The Panthers are a run-heavy team with the 10th-best ground game in the league, and they’re facing a team that is 24th against the run and is giving up 24.2 points per game. The Saints throw the ball 59 percent of the time with the 21st-ranked passing game in the league, and they’re facing a team that is 18th against the pass and is giving up 22.8 points per game. Expect these teams to score enough points to push the score over the total. The Panthers and Saints played over the total in two of their last three meetings.
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