Denver Broncos vs. Philadelphia Eagles Picks and Prediction for Sunday, October 5, 2025
Use Code WWWC As the calendar flips to October and the leaves begin to turn, week 5 of the 2025 NFL season brings us an interconference matchup when the Denver Broncos battle the Philadelphia Eagles in the City of Brotherly Love on Sunday afternoon and we have you covered with our Broncos vs. Eagles prediction. Denver picked up a 28-3 home win over Cincinnati on Monday Night Football in their previous contest, covering the line as a 7.5-point favorite. Philadelphia held off Tampa Bay 31-25 on the road last Sunday in their previous game, covering the line as a 3.5-point favorite. In the all-time regular season series between the teams, the Eagles own a 9-5 advantage and have won the last two meetings, including a 30-13 road win in the most recent matchup on November 14, 2021. Read more about this Broncos vs. Eagles prediction! Don’t get sacked this football season! Try our NFL Picks!
Broncos Looking for Second Straight Victory
Denver bounced back from a pair of last-second losses as they dropped the hammer on the Bengals at home Monday night. The Broncos improved to 2-2 on the season and stood tied for second in the AFC West, one game behind the Chargers. Against Cincinnati, Denver gave up a field goal on the opening possession but shut the Bengals down the rest of the way. The Broncos scored the game’s final 28 points and dominated the remainder of the contest. Denver rolled up a commanding 512-159 advantage in total offense, owned a 29-9 edge in first downs and owned a 37:58 to 22:02 margin in time of possession. Those massive numbers made up for the fact that the Broncos committed the game’s lone turnover.
The Broncos enter this game 16th in the league in passing offense with an average of 211.3 yards per game through the air and they stand 5th in rushing offense by putting up 143.3 yards per contest. Denver is 16th in scoring offense with an average of 24 points per game, while they are 2nd in scoring defense by allowing an average of 16.8 points a game. Bo Nix is 90 of 137 passing for 861 yards with seven touchdowns and four interceptions while getting sacked three times. He is third on the team in rushing with 25 carries for 78 yards and a score. J.K. Dobbins (57 carries, team-high 323 yards, three TD) and RJ Harvey (27 carries, 138 yards) are the top two backs in the system. Courtland Sutton leads the team with 18 receptions for 266 yards plus three scores on the year. Troy Franklin (18 receptions, 196 yards, TD), Marvin Mims Jr. (12 catches, 109 yards, TD), Harvey (nine catches, 69 yards, TD), and Evan Engram (eight grabs, 62 yards) are solid targets. Wil Lutz hit 12 of 12 extra point attempts and is four of five on field goal attempts with a long of 42 this season.
Tight end Nate Adkins (concussion) did not practice on Wednesday and was limited on Thursday. Center Quinn Meinerz (illness) missed practice on Thursday. Mims Jr. (hip/ankle) and linebacker Jonah Elliss (ribs) were each limited on Wednesday and Thursday. Watch for updates on their status as the injury report is updated.
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Philadelphia Trying to Remain Unbeaten
Philadelphia started strong and built a big halftime advantage before seeing its offense sputter as it had to hang on for the victory on the road over Tampa Bay last week. The Eagles improved to 4-0 on the season and own a two-game lead over Washington in the NFC East. Against Tampa Bay, Philadelphia jumped in front 14-0 less than eight minutes into the game and held a 24-6 advantage at the half. The Eagles still led 31-13 with 3:51 to play in the third quarter and held off the Buccaneers for the win. Philadelphia was outgained 376-200 in total offense, gave up 18 first downs while picking up 16, and lost time of possession by a 31:52 to 28:08 margin, yet managed to prevail. The Eagles forced a pair of turnovers and scored on a blocked punt while not committing a turnover in the contest.
For the year, the Eagles are 31st in the league in passing offense with 138 yards per game and 15th in rushing offense with 113.5 yards per contest. Philadelphia stands 7th in the league in scoring offense with 27 points per game, while they are 15th in the league in scoring defense by allowing 22 points per contest. Jalen Hurts has completed 70 of 101 passes for 609 yards with five touchdowns against no interceptions while getting sacked nine times. He is second on the team on the ground with 41 carries for 179 yards and four scores. Saquon Barkley leads the team on the ground with 77 carries for 237 yards and three scores. AJ Dillon (nine carries, 46 yards) and Will Shipley (three carries, 26 yards) are the only other players to run the ball offensively this season for the Eagles. DeVonta Smith leads the team with 17 receptions for 158 yards and a score on the year. A.J. Brown (14 catches, 151 yards, TD), Dallas Goedert (12 grabs, 114 yards, three TD), Barkley (14 catches, 70 yards), and Jahan Dotson (five grabs, 70 yards) are all useful targets. Jake Elliott is 12 of 12 on extra point attempts and four of four on field goal attempts with a long of 58 this season.
Goedert (knee) missed practice on Wednesday and was limited on Thursday. Tight end Grant Calcaterra (illness) missed practice Thursday, while linebacker Nakobe Dean (knee) was limited both days. Watch for updates on their statuses leading to kickoff.
Broncos vs. Eagles Pick
Spread Pick for Broncos vs. Eagles
- Broncos +4.5 (4 units)
Philadelphia is unbeaten and they are at home here, but the fact remains that their passing attack has been subpar this season. Hurts went zero for eight in the second half against the Buccaneers and now faces a Denver defense that can get after the passer with reckless abandon. Denver has been in every game this season and their two losses are by a combined four points. The Broncos should be able to keep the Eagles contained for the most part offensively, and they can make plays on offense. Philadelphia may well win this game, but it’s a tight one and getting the plus side of a field goal is too enticing. Take the points and the Broncos here.
Over/Under Pick for Broncos vs. Eagles
- Under 44.5 (4 units)
Denver comes into this game having stayed under the number in three of their four games this season. The Broncos split their two road games in relation to the total this season, going over the number against the Colts and staying under the mark in their loss to the Chargers. Philadelphia split their four games in relation to the total this season. The Eagles also split their two home games concerning the number, staying under against Dallas in the season opener and going over in their win over the Rams. Denver’s defense is stingy, and they should help keep this game under the mark.
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