Kansas City Chiefs vs. Tennessee Titans Picks and Prediction for Sunday, December 21st, 2025
Use Code WWWC The Kansas City Chiefs (6-8, 5-9 ATS, 4-10 O/U) take on the Tennessee Titans (2-12, 6-8 ATS, 9-5 O/U) in an AFC bout on Sunday afternoon, and we have you covered with the prediction. The Chiefs were hit with a loss to the Chargers last week. The Titans dropped a road meeting against the 49ers in their previous action. These squads last met in 2022 in a game the Chiefs won in overtime.
Can the Titans post their third win of the season on Sunday afternoon? Continue reading for the Chiefs vs. Titans prediction. Do you need a boost in your handicapping? Try our NFL Betting Picks!
Chiefs Out of Playoff Contention
The Kansas City Chiefs are winding down the season. They have been eliminated from playoff contention for the first time in 10 years. The Chiefs have not been able to generate enough points in the past five or so games, and it has cost them in the standings. They have dropped five of their past six games. The only win in that span was an OT win against the Colts. The Chiefs were hit with a 20-10 home loss by the Texans two weeks ago and a narrow 16-13 home defeat to the Chargers last week in a clash that had the Chiefs as six-point favorites. The Chiefs have not covered the spread in any of their past five games.
Patrick Mahomes had a hand injury and is out for the remainder of the season. The star QB has recorded 3586 passing yards and a 22:11 TD to INT ratio. It will be Gardner Minshew under center. Minshew has started plenty of games in his career. The 29-year-old QB has only attempted five passes this season. Minshew has posted a 68:35 TD to Int ratio in his career.
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The Chiefs might run more than usual with Mahomes out. Kareem Hunt only managed 12 yards last week and leads the squad with 557 rushing yards on the season. The receiving core has depth. Travis Kielce has consistently produced all season. He had 70 yards last week and has netted 797 receiving yards on the year. Rasheen Rice is next up with 571 yards. The KC offense posted just 239 total yards last week. This brings their season average to 357 yards per game.
The Chiefs' defense has been a strength most of the season. The unit kept the Chargers to only 295 total yards last week. They are conceding 303 yards per game. They have conceded 22 or fewer points in four of their past five games. Nick Bolton has been a beast, making 123 combined tackles. The pass defense is 15th while the rush defense is marked fifth.
Kansas City is averaging 23.4 points on the season, ranking them 15th. The Chiefs are conceding an average of 19.1 points, placing them fifth in the NFL.
Titans Seek Third Win of Season
The Tennessee Titans are seeking just their third win of the season. Tennessee is obviously having a poor season, but the good news is that they have been competitive in many of their recent defeats. They only lost by six against the Seahawks and posted a 31-29 road win against the Browns in their first game of December. The success did not last in a 37-24 road loss to the 49ers last week. The Titans were big 12-point dogs in that one. The Titans have covered the spread in three of their past five games.
Cam Ward has displayed some improvement, but has not broken out. The 2025 #1 pick has reached 200 passing yards in only six games this season. Ward had 170 yards last week and has delivered 2638 passing yards and an 11:7 TD to INT ratio on the season. He has added 129 yards on the ground.
Tennessee will run more than pass. Tony Pollard has been the biggest offensive threat on the squad. The veteran running back has surpassed 100 rushing yards in two straight games, including 160 yards against the Browns, and has recorded 847 rushing yards on the year. The receiving core is weak. They only have one player with more than 300 yards. Chig Okonkwo has surpassed 50 receiving yards in three games this season. The 26-year-old WR has contributed with 459 receiving yards on the season. Elic Ayomanor has 370 yards. The Tennessee offense posted 306 total yards last week. They are averaging 250 yards per game.
The Titans' defense has been exposed in the recent defeats. They have squandered 25 or more points in five of their past six games. They gave up 430 total yards against San Francisco, dipping their season average to 356 yards per game. Linebacker Amani Hooker is having an outstanding season. He has made 76 tackles. The pass defense is 25th, while the rush defense is a bit better, coming in at 20th.
Tennessee is scoring an average of 16.1 points, marking them 31st. The Titans are squandering an average of 28.1 points, pegging them 28th in the NFL.
Chiefs vs. Titans Pick
Spread Pick for Chiefs vs. Titans
- Tennessee Titans +3 (5 units)
The Kansas City Chiefs are a dejected group after being eliminated from playoff contention after their defeat to the Chargers last week. The Chiefs have been horrendous, posting a 1-5 record in their past six games. The Tennessee Titans have been competitive. They only lost by three points against the Texans and six against the Seahawks within their past five games.
Furthermore, KC is playing without QB Patrick Mahomes. Gardner Minshew is under center instead. The veteran QB has not played yet this season. KC could run more than usual, which is ideal for the Titans, whose top strength on defense is the rush defense. The Titans have covered the spread in three of their past four home games, and they should cover again.
Over/Under Pick for Chiefs vs. Titans
- Over 37 (5 units)
I expect plenty of scoring. The Chiefs’ defense has been subpar. They have conceded an average of 22 points in their past five games, above their season average of 19 points. Tennessee is scoring more points, scoring 55 points in its past two games.
In addition, the Titans' defense has been exposed. They have squandered 25 or more points in five of their past six games, including 55 points in their past two home games. Even without Mahomes, the offense should do damage in the air against a weak pass defense that stands 25th. The over is 5-2 in the Chiefs' past seven road games against the Titans.
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