Los Angeles Chargers vs. Jacksonville Jaguars Picks and Prediction for Sunday, November 16, 2025
Use Code WWWC The NFL season rolls on as the week 11 slate brings action to the Sunshine as a pair of squads currently in the AFC playoff picture search for a win when the Los Angeles Chargers take on the Jacksonville Jaguars Sunday afternoon and we have you covered with our Chargers vs. Jaguars prediction. Los Angeles comes in off a 25-10 home victory over the Steelers last Sunday, covering the line as a three-point favorite in their previous contest. Jacksonville fell 36-29 on the road to Houston last Sunday, failing to cover the line as a one-point underdog in their previous contest. In the all-time regular season series between the teams, the Chargers own a 9-4 advantage, but the Jaguars picked up a 38-10 win on the road in the most recent meeting on September 25, 2022. Read more about this Chargers vs. Jaguars prediction! Don’t get sacked this football season! Try our NFL Picks!
Los Angeles Seeking Fourth Straight Win
Los Angeles won their third straight game as they took down Pittsburgh at home in their previous contest last Sunday. The Chargers improved to 7-3 on the year and stood second in the AFC West, one game behind the Broncos for the top spot. Against Pittsburgh, Los Angeles trailed 3-0 in the first quarter but scored the next 25 points to take control of the game. The Chargers kept the Steelers out of the end zone until less than three minutes remained in the game. Los Angeles owned a 314-221 advantage in total offense, picked up 18 first downs while allowing 11, controlled the clock by a 37:35 to 22:25 margin and forced three turnovers while not committing any.
On the year, the Chargers are 7th in the league in passing offense with 245.4 yards per game, while they are 10th in rushing offense with an average of 123.1 yards per contest. Los Angeles is 13th in the league in scoring offense with 24 points per contest and 8th in scoring defense by allowing an average of 20.3 points per contest. Justin Herbert has hit 240 of 358 passes for 2,610 yards with 19 touchdowns and eight interceptions on the year. He has been sacked 33 times while ranking second on the team with 324 yards plus a score on the ground. Trey Lance is three of four for 44 yards as the backup. Kimani Vidal leads the team with 91 carries for 404 yards and two scores on the ground. Omarion Hampton (66 carries, 314 yards, two TD), Jaret Patterson (21 carries, 75 yards) and Najee Harris (15 carries, 61 yards) are next in line. Ladd McConkey is second on the team with 51 receptions for 631 yards and four scores. Keenan Allen (52 receptions, 539 yards, four TD), Quentin Johnston (37 catches, 502 yards, six TD), tight end Oronde Gadsden II (35 grabs, 466 yards, two TD) and Tre’ Harris (15 catches, 125 yards, TD) are solid secondary options in the passing game. Cameron Dicker is 23 of 23 on extra point attempts and 23 of 25 on field goal attempts with a long of 59 this season.
Tackle Bobby Hart (knee), defensive backs Tarheeb Still (knee) and Elijah Molden (knee), Johnston (shin) and fullback/defensive lineman (chest) are each questionable for this contest. Watch for updates leading to kickoff.
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Jaguars Hoping to Rebound After Blown Opportunity
Jacksonville was cruising along for three quarters on the road against Houston but imploded in the final stanza, winding up with the loss. The Jaguars fell to 5-4 on the season and stood second in the AFC South, though they own a wild-card spot. Against Houston, Jacksonville was rolling as they were up 10-0 after the opening quarter, 17-0 in the second quarter, 20-10 at the half and 29-10 after three quarters. The Jaguars fell apart in the fourth quarter, getting outscored 26-0, to wind up with the loss. Jacksonville was outgained 412-213 in total offense, gave up 27 first downs while picking up 19 and lost time of possession by a 31:00 to 29:00 margin. Both teams turned the ball over twice, with the Jaguars scoring on a punt return while giving up a fumble return for a score.
On the season, Jacksonville is 19th in the league in passing offense with 204.6 yards per contest and 14th in rushing offense with 120.3 yards per game. The Jaguars are 18th in the league in scoring offense as they average 22.8 points per contest and stand 20th in scoring defense by allowing 24.4 points per contest. Trevor Lawrence has completed 188 of 316 passes for 1,998 yards with 10 touchdowns and seven interceptions on the year. He adds 172 yards plus four scores on the ground. Travis Etienne Jr. leads the Jaguars on the ground with 135 carries for 656 yards and three scores. Bhayshul Tuten (45 carries, 164 yards, two TD) and LeQuint Allen (five carries, 32 yards) are net in line this season. Brian Thomas Jr. leads the team with 30 catches for 420 yards plus a score on the season. Parker Washington (28 catches, 330 yards, two TD), Travis Hunter Jr. (28 grabs, 298 yards, TD), Dyami Brown (19 receptions, TD) and Brenton Strange (20 catches, 204 yards) are the only other players with more than 175 receiving yards this season. Cam Little has hit 19 of 20 extra point attempts and 16 of 20 field goal attempts with a long of 68 this season.
Tight ends Hunter Long (hip/knee) and Strange (hip), offensive lineman Anton Harrison (knee/ankle), along with cornerback Jordan Lewis (neck) are all out here. Thomas Jr. (ankle) is questionable for this contest. Hunter was placed on the IR and will miss the season due to surgery on his right knee.
Chargers vs. Jaguars Pick
Spread Pick for Chargers vs. Jaguars
- Chargers -3 (4 units)
After seeing Jacksonville crumple in the fourth quarter against a Houston team playing their backup quarterback, it’s tough to have a ton of faith in them here. Hunter Jr. is done for the season, while Thomas Jr. has regressed from last season’s stellar rookie campaign. Los Angeles stifled the Steelers last week and has won three straight games entering this contest. A West Coast team playing a 1 pm ET start is always concerning, but the Chargers are relatively healthy at the skill positions, which is important. Look for Los Angeles to take advantage of a suddenly reeling Jacksonville squad to come up with the road victory.
Over/Under Pick for Chargers vs. Jaguars
- Over 43.5 (4 units)
Los Angeles has split their 10 games in relation to the total this season. The Chargers split their four road games in relation to the total though they have gone over the number in four of their last five games overall, including their last two road tilts. Jacksonville has seen the over post a 5-4 mark in their nine games, though the home/road splits are interesting. The Jaguars have gone over the total in all four of their road games but stayed under the mark in four of their five home games. After seeing Jacksonville give up 26 fourth-quarter points to Houston, the potential for big outbursts is there. Take the over here as the Chargers likely put up 24 to 27 points in the win.
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