Los Angeles Chargers vs. Tennessee Titans, Preview, Odds, Picks and Prediction, Sunday, November 2nd, 2025
Use Code WWWC The Los Angeles Chargers (5-3) will be in Nashville on Sunday to take on the struggling Tennessee Titans (1-7) in a Week 9 AFC matchup. These teams have faced off in each of the past three seasons, with the Chargers holding a 2-1 straight-up edge and a 1-1-1 mark against the spread. Last year, Los Angeles rolled to a 27-17 home win as an eight-point favorite.
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Chargers in playoff position
The Chargers are second in the AFC West, tied with the Chiefs and one game behind the Broncos. If the season ended today, they’d be the No. 6 seed in the AFC. Against the spread, the Chargers are just 3-4-1, and they are 4-4 on totals.
The Chargers’ offense has been one of the league’s most explosive, ranking fourth in both total offense (378.5 yards per game) and passing (255.4 yards per game). They sit 12th in rushing (123.1 yards per game) but just 16th in scoring (23.5 points per game).
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Justin Herbert leads the NFL with 2,140 passing yards. He also ranks eighth in QBR (68.6), with 16 touchdowns and seven interceptions. The leading receivers are Keenan Allen (479 yards, four touchdowns) and Ladd McConkey (468 yards, three touchdowns). McConkey is questionable for Sunday, and also on the injury list is rookie running back Omarion Hampton, who leads the team with 314 rushing yards and will not play Sunday. CB Taheeb Still (knee) is doubtful and OG Mekhi Becton (knee) is questionable.
The Los Angeles defense ranks seventh with 296.9 yards allowed per game and sixth against the pass (184.5 yards per game). The scoring defense is 12th, allowing just 21.6 points per game.
The losing continues
It’s been another terrible season in Tennessee. The Titans are just 1-7 overall, 2-6 ATS, and 5-3 to the over. Rookie quarterback Cam Ward has endured growing pains, ranking 32nd in QBR (25.7) with 1,615 passing yards (17th), five touchdowns, and six interceptions.
The offense has been dreadful, ranking last in the league in total yards (248.8), rushing (80.4), and scoring (13.8 points per game), while sitting 31st in passing (168.4). Tony Pollard leads the team with 424 rushing yards and two touchdowns. When it comes to Ward's targets, Calvin Ridley has a team-best 290 receiving yards, but he is also questionable for Sunday. Next up are Eric Ayomanor (277 yards), and tight-end Chig Okonkwo (271 yards).
Defensively, the Titans haven’t been any better. Tennessee ranks 26th in total defense (358.4 yards per game), 26th against the run (142.6 yards per game), and allows 28.8 points per game (30th). S Xavier Woods (hamstring), LB Arden Key (quad), and CB Darrell Baker Jr (concussion) are questionable, though Baker Jr. was a full participant in practice on Thursday.
Chargers vs Titans Prediction
Spread Prediction for Chargers vs. Titans
- Chargers -9.5 (5 units)
The Chargers offense has been surging, and I don't like the Titans' chances of keeping up in this game. Even with McConkey questionable and Hampton out, I trust the Chargers more, and the Titans also have a banged-up Calvin Ridley. Tennessee's home struggles are impossible to ignore, as they have gone 0-11 ATS in Nashville since last season, and the Chargers are 8-5 ATS on the road over that same stretch.
One day, the Titans will cover again, but I’m not going to overthink this or chase that Titans cover. I can not take a team that is on a 4-21 ATS run.
Back the Chargers.
Total Prediction for Chargers vs. Titans
- Over 43.5 (4 units)
The Chargers have scored at least 24 or more points in their last three games, while the Titans’ defense has allowed at least 31 points in all three of their home outing this season. With Justin Herbert leading the passing game, expect to see explosive offensive plays, and even if Tennessee can’t keep pace, Los Angeles can carry most of the heavy lifting. The over is 4-0-1 in the Titans’ last five home games, and I will take the over.
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