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Los Angeles Rams vs Carolina Panthers Picks, Prediction, Odds, and Line Movement for Saturday, January 10, 2026

By: Liam Keating Published 01/10/2026, 02:47 AM ET
Rams vs. Panthers prediction

The NFL playoffs begin this weekend with a big time NFC clash on Saturday, Jan. 10. Read our Los Angeles Rams vs Carolina Panthers predictions our other NFL Picks! The Rams are the No. 5 seed with a 12-5 record. They are coming off a big win against the Cardinals to close out the regular season. The Panthers lost to Tampa Bay, but they were able to cling the NFC South division with an 8-9 record as they are the No. 4 seed. The Panthers defeated the Rams during the regular season in a really close game. The first round of the playoffs will begin with kick-off set for 4:30 P.M. EST.

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Rams look to bounce back after regular season loss to Carolina

The Rams are 12-5 overall this season. They are the No. 5 seed in the NFC as they are the top seeded wild card team. Los Angeles finished in second place in the NFC West as they were a few games back of divisional champions Seattle. The Rams finished the season with a 3-3 record. One of those losses was a 31-28 defeat to Carolina on the road in Week 13.

In their last game, the Rams defeated Arizona 37-20 at home on Sunday, Jan. 4. The Rams led 16-6 at halftime, but the Cardinals scored back-to-back touchdowns in the third quarter to take a 20-16 win. But, quarterback Matthew Stafford sling three touchdowns in the final 16 minutes to take the win. Stafford threw for 259 yards on 25-for-40 passing with four touchdowns. Running back Karen Williams added 60 yards while Tyler Higbee had a team-high 91 yards and a touchdown.

In Week 13, Stafford turned the ball over three times with two interceptions and one pick to allow the Panthers to secure the win. The Rams went 2-for-5 on third-down as the Panthers took advantage of every chance that the Rams gave them.

Stafford has thrown for 4,707 yards, 46 touchdowns and eight interceptions on the year. Williams has rushed for 1,252 yards and 10 touchdowns on the year. Puka Nacua is leading the receiving corps with 1,715 yards and 10 touchdowns.

On defense, the Rams are led in tackles by linebacker Nate Landman with 132 tackles. Byron Young leads the team with 12 sacks. The defense has forced 22 turnovers with Landman leading the team with four interceptions.

Los Angeles is averaging 30.5 points per game, which is the best mark in the league. They are passing for 268.1 yards per game, which also ranks first. The Rams are averaging 126.6 yards per game on the ground, which places them seventh-best.

On defense, the Rams are allowing 20.4 points per game, which ranks 10th in the league. They are the 19th ranked pass defense, allowing 216.7 yards per game. The Rams are allowing 110.8 rushing yards per game, which ranks 12th.

The Rams are 12-5 against the spread this season. Los Angeles is 11-4 against the spread when they have been favored. They are also 2-0 against the spread as a double-digit favorite. The over is 10-6-1 when the Rams have played this season. The over is 7-2 when the Rams have played on the road.

Key injuries 

  • OL Kevin Dotson (ankle), out
  • WR Jordan Whittington (knee), out
  • TE Terrance Ferguson (hamstring), questionable
  • CB Josh Wallace (ankle), questionable 

Carolina wins NFC South with below .500 record

Carolina is 8-9 overall this season. The Panthers are the No. 4 seed as they clinched the NFC South and won the division. Carolina won the division after earning the tiebreaker over Tampa Bay and Atlanta, who both held the same record. The Panthers are 5-3 when playing at home, which included a big home win over the Rams earlier in the year. The Panthers finished the season losing four of their last six games.

In their last game, the Panthers lost 16-14 to the Buccaneers on the road on Saturday, Jan. 3. Baker Mayfield threw a touchdown in the first quarter, which allowed Tampa Bay to go ahead 10-0 early. They stayed ahead for the entirety of the game as Carolina cut into the lead in the with a touchdown in the final 2:27, which wasn’t enough for the win. Quarterback Bryce Young threw for 266 yards with touchdowns and one interception. The rushing attack went for a total of 19 yards on 14 carries.

Earlier this season, the Panthers defeated the Rams 31-28 at home in the regular season. The Panthers trailed 21-17 at halftime as they outscored Los Angeles 14-7 in the second half. Young tossed a 43-yard touchdown to Tetairoa McMillan to give them the win in the fourth quarter. Carolina’s defense force four turnovers, which was key in the victory.

This season, Young has thrown for 3,011 yards with 64% passing percentage. He’s thrown 23 touchdowns and 11 interceptions on the year. Rico Dowdle is rushing for 1,076 yards with six touchdowns on the year, too.

On Defense, Christian Rozeboom has a team-high 122 tackles. Nic Scourton and Derrick Brown both lead the team with five sacks. The defense has forced 21 turnovers with Jaycee Horn leading the team with five picks.

Carolina is averaging 18.3 points per game, which ranks 27th in the league. They are the seventh-worst passing offense as they are averaging 179.3 passing yards per game. The Panthers are averaging 116.3 yards per game, which ranks 19th.

On defense, Carolina is allowing 22.4 points per game, which ranks 15th in the league. They are allowing 203.9 yards per game, which ranks 15th. The Panthers also rank 20th in rush defense surrendering 123.3 yards per game.

Carolina is 10-7 against the spread this season. The Panthers are 5-3 against the spread when they are playing at home. They are 2-0 against the spread when they have been double-digit underdogs. The under is 10-7 when Carolina has played this season. The total is 4-4 when Carolina has played at home. The total is 3-3 when the total has been set at 44 points or more this year.

Key injuries 

  • Chandler Zavala (calf), out

Los Angeles Rams vs Carolina Panthers Picks

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Rams vs Panthers Spread Pick

  • Los Angeles Rams -10 (5 units)

The Rams and the Panthers played an exciting game in the regular season. The Panthers came away with the win late in the contest as Matthew Stafford turned the ball over three times, which were killers to the offense that drove the ball at will. That is the main the key in this game. The Rams cannot turn the ball over and they will come away with a big victory. The Panthers have not looked their best over the past month as offensive and defensive inconsistencies have plagued the team. It was evident in last week’s loss to Tampa Bay that would have secured a playoff berth. Instead, the team had to wait for a Falcons victory. In a big moment, the Panthers could not step up to the plate and that will happen in this game as Stafford tries to bring the Rams back to the Super Bowl. Los Angeles is 11-4 against the spread when they have been favored. They are also 2-0 against the spread as a double-digit favorite.

Take the Rams to cover.

Rams vs Panthers Over/Under Pick

  • Over 45.5 (5 units)

The over hit easily when the Rams and the Panthers faced each other in the regular season. The two defenses could not stop each other, even when turnovers occurred. This should happen again in this game as the Rams are the No. 1 scoring offense in the sport. The Panthers should be able to score with their passing attack against a Rams defense that is allowing the 19th most yards in the league. The total is 4-4 when Carolina has played at home. The over is 7-2 when the Rams have played on the road.

Take the over on Saturday. 

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