New Orleans Saints at Carolina Panthers Preview, Odds, Picks and Prediction, Sunday, November 9, 2025
Use Code WWWC It’s an NFC South battle between two teams on the opposite side of the winning spectrum on Sunday, Nov. 9. Read our New Orleans Saints vs Carolina Panthers prediction along with our other NFL Picks! The Saints are 1-8 overall this season. They have lost four straight Ames with every road loss coming by double-digits. The Panthers are 5-4 and they have won four of their last five games. Carolina is coming off a great win against the Packers last week. These two teams will meet with kick-off set for 1 P.M. EST.
Saints vs. Panthers Matchup
New Orleans in the NFC South basement
New Orleans is 1-8 overall this season. They are in last place in the NFC South, and they have the worst record in the conference, too. The Saints are winless when playing on the road, too. Each road loss has been separated by double-digits each time. The Saints are also on a four-game losing streak.
In their last game, the Saints lost 34-10 to the Rams on the road on Sunday, Nov. 2. Rookie Tyler Shough threw for 176 yards on 15-for-24 passing with a touchdown and an interception in the loss. The Saints' offense accrued just 10 first downs compared to Los Angeles’ 30 first downs. The offense for the Saints accumulated just 224 total yards while the defense gave up 438 yards to the Rams.
Shough will get his second start of the season since taking over from Spencer Rattler. Alvin Kamara is leading the rushing yards with 377 on the year, while he has also scored one touchdown. Chris Olave is the top receiver for the team with 560 yards and three touchdowns.
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On defense, the Saints are led in tackles by Demario Davis with 84 tackles. Carl Granderson is the top pass rusher with 4.5 sacks. The defense has forced 10 turnovers on the year, too.
The Saints are averaging 15.3 points per game, which ranks second-worst in the league. New Orleans is rushing for 89.6 yards per game, which ranks fifth-worst. They rank 22nd in passing yards as they are going for 197.6 yards per game.
On defense, New Orleans is allowing 27 points per game, which ranks 24th. They are the 24th-ranked rush defense, giving up 129.4 yards per game. The Saints are giving up 203.9 passing yards per game, placing them 14th.
New Orleans is 2-7 against the spread this season. They are 1-3 against the spread when they have played on the road. The Saints are 0-4 against the spread when they have been six points or less underdogs. The under is 5-3-1 when New Orleans has played. The over is 2-1-1 when they have played on the road. The under is 4-2-1 when the Saints have played against NFC teams.
Tackle Taliese Fugal is out for the game. Running back Alvin Kamara, tight end Jack Stoll, defensive end Jonah Williams and defensive tackle Bryan Bresee are all questionable.
Carolina riding high as they are over .500
Carolina is 5-4 overall this season. The Panthers are in second place in the NFC South as they sit behind Tampa Bay with a 6-2 record. Carolina is 3-1 when they have played at home. The Panthers have won four of their last five games, with the lone loss coming against Buffalo.
In their last game, the Panthers defeated the Packers 16-13 away from home on Sunday, Nov. 2. Rico Dowdle scored a short rushing touchdown to give Carolina a 13-6 lead going into the fourth quarter. Green Bay was able to tie the game late in the fourth quarter, but the Panthers secured the wild road win thanks to a 49-yard field goal.
Quarterback Bryce Young threw for 102 yards on 11-for-20 passing with zero touchdowns and one pick. Dowdle had a huge game with 130 yards and two touchdowns.
Young has thrown for 1,390 yards and has completed 61% of his passes this season. He has thrown for 11 touchdowns and six picks on the year. Dowdle has been a fantastic addition to the Panthers with 735 yards and four touchdowns on the year. Tetairoa McMillan is the top target with 558 yards and two touchdowns on the year.
On defense, Christian Rozeboom leads the team with 77 tackles, which is 22 more tackles than the field. Derrick Brown has a team-high three sacks, too. The defense has forced nine turnovers, with Jaycee Horn leading the team with three picks.
Carolina is averaging 18.9 points per game which ranks 27th. They are the fifth-best rushing attack with 139.8 rushing yards per game. The Panthers are passing for 170.9 passing yards per game, which places them third-worst.
On defense, the Panthers are allowing 22.8 points per game, placing them 16th. Carolina is the 15th-ranked pass defense, giving up 205.9 passing yards per game. They are the 18th-ranked rush defense, too. The Panthers are allowing 110.8 rush yards per game.
Carolina is 6-3 against the spread this season. They are 3-1 against the spread when they have played at home. The Panthers are 1-0 against the spread as a favorite. The over is 5-4 when the Panthers have played. The over is 3-1 when the Panthers have played at home. The under is 1-0 when the total has been set at 39 points or less.
Guard Chandler Zavala is out for the game. Wide receiver Brycen Tremayne and wide receiver Tetairoa McMillan are both questionable.
New Orleans Saints vs Carolina Panthers Picks
Saints vs Panthers Spread Pick
- Carolina -5.5 (4 units)
The Panthers have been one of the surprise teams of the season. They are continually playing well, winning four of their last five games. This stretch has been highlighted by the team’s win over the Packers last week, as the defense was impressive. Carolina ranks 16th in scoring defense and 15th in pass defense. Both of these marks will be good enough to dominate a New Orleans team that has been really poor on the road.
They have lost each road game by at least double digits. They are now starting rookie quarterback Tyler Shough, who struggled in his first start last week against the Rams, where the Saints lost by 24 points. The Saints' defense ranks 24th in defending the rush, which will be problematic against a Panthers team that has only improved their running numbers. Rico Dowdle has been great this year and has Carolina ranked fifth best in rush yards per game. Momentum is on the side of Carolina, along with a strong rushing game; the Panthers will get the win. New Orleans is also 0-4 against the spread when they have been six points or less underdogs
Saints vs Panthers Over/Under Pick
- Under 38 points (5 units)
The under is 1-0 when the total has been set at 39 points or less for Carolina games this season. The under is 4-2-1 when the Saints have played against NFC teams, too. This is going to be a really low-scoring game with New Orleans’ very poor offensive statistics against a Panthers defense that ranks 16th in scoring. The Panthers' offense ranked as one of the best rush offenses, will have the clock rolling all game long.
Take the under on Sunday.
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