New Orleans Saints vs. Seattle Seahawks Prediction and Picks - September 21, 2025
Use Code WWWC The New Orleans Saints face the Seattle Seahawks in Week Three of the NFL season. The Saints are 0-2 and look like one of the worst teams in the NFL while the Seahawks are coming off a big win on the road and hope to sneak up on a few teams early on this season. Who will win this game? Check out our Saints vs Seahawks prediction!
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Saints hope to improve across the board
The Saints are off to an awful start to the season, with their offense letting them down and scoring only 17 points per game. The issues start under center with quarterback Spencer Rattler off to an underwhelming start, with only 421 passing yards and three touchdowns, while the receivers have also disappointed, with nobody eclipsing 100 yards on the season yet. The hope is that Alvin Kamara steps up and helps out the run game, as the veteran running back has only 144 rushing yards and a touchdown through two games.
The offense has let the Saints down, but the defense has also played poorly, allowing 23 points per game. Defensive end Carl Granderson has 3.5 sacks, while inside linebacker Demario Davis has 20 tackles, but the rest of the defense has struggled. The hope is that Isaac Yaidom, Jordan Reid, and Julian Blackmon step up in the secondary and start creating turnovers, as the Saints have yet to force an interception this season.
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Seattle hopes defense fuels another victory
The Seahawks are off to a promising start with their offense stepping up and scoring 22 points per game. They beat Pittsburgh in their last game 31-17, which was an impressive road victory. Sam Darnold has had a shaky start with 445 passing yards, two touchdowns, and two interceptions, but the rest of the offense has stepped up to make up for it. Jaxson Smith-Njigba and Cooper Kupp have combined for 332 receiving yards while Kenneth Walker has stepped up in the run game with 125 rushing yards and a touchdown.
The offense has stepped up but the defense has carried the Seahawks, allowing only 17 points in each of the last two games. Byron Murphy and Jarren Reed have combined for 19 tackles and 2.5 sacks upfront, while Ernest Jones has 18 tackles and an interception from the linebacker position. What’s made the defense stand out is the secondary, with Coby Bryant, Josh Jobe, and Derion Kendrick combining for three interceptions and five interceptions.
Saints vs Seahawks Prediction
- Seahawks -7 (4 Units)
The Seahawks are off to a strong start and look to dominate this game against one of football’s worst teams. The Seahawks, who average 22 points per game, should pick apart the Saints' defense with Sam Darnold finding open receivers down the field while Kenneth Walker gashes the Saints on the ground. The Seahawks should limit the Saints offense with Jarren Reed creating pressure with Coby Bryant and Josh Jobe breaking up passes down the field. The Seahawks should win the game and cover the spread in a dominant performance at home.
- Under 41.5 (5 Units)
The Seahawks are led by a great defense, and this game looks to be a low-scoring one from the first quarter. The Saints should limit the Seahawks' offense with Carl Granderson creating pressure in the trenches while Demario Davis limits big plays in the middle of the field. The Seahawks, who allow only 17 points per game, should eliminate the Saints offense, which averages only 17 points per game, with Jarren Reed and Byron Murphy creating pressure upfront while Coby Bryant, Josh Jobe, and Derion Kendrick break up passes down the field and force turnovers. The Under should cover in a low-scoring game with both defenses stepping up.
Take the Under on 41.5 runs.
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