Packers vs. Lions Odds, Preview, Picks, and Prediction for Thursday, November 27, 2025

The Detroit Lions will host the Green Bay Packers on Thursday at Ford Field in Week 13 NFL action, pitting NFC North rivals. We have you ready to go with our Packers vs. Lions prediction, preview, and picks. The Thanksgiving Day game kicks off at 1:00 p.m. ET.

The Lions are 2.5-point spread favorites, and the game total is 49.5 points scored.

Detroit and Green Bay met in Week 1 at Lambeau Field, a game the Packers led from start to finish. QB Jordan Love passed for two touchdowns and DE Micah Parsons recorded a sack in his first game with Green Bay to lead the team to a 27-13 victory. The Lions won both matchups last season and are 6-4 straight-up (6-4 ATS) over the previous ten meetings. The over/under was split 5-5 in those games. If you want the Packers vs. Lions prediction, read on and check out our NFL Picks to beat the sportsbooks!

Did Packers turn a corner against Vikings?

Green Bay (7-3-1 SU, 4-7 ATS, and 4-6-1 O/U) has won consecutive games, bouncing back from losses to Carolina and Philadelphia.

The Packers covered as 6.5-point spread favorites in their 23-6 victory over Minnesota, sacking Vikings QB JJ McCarthy five times and forcing three turnovers. Green Bay dominated the time of possession by nearly 15 minutes, as Minnesota totaled just four net yards in the second half. RB Emanuel Wilson, who was filling in for injured starter Josh Jacobs, rushed for 107 yards and scored two touchdowns. The Packers are one game behind the Bears in the division standings and will face them twice over the next month.

“I've never called the same run so many times consecutively,” Packers coach Matt LaFleur said. “It was like 3 yards and a cloud of dust, but it was effective. Bottom line, I just thought the way our defense was playing, we just took the air out of the ball and said, ‘Go win it for us.’ ”

Jordan Love leads the Green Bay aerial attack with 2,560 passing yards and a 15:3 TD:INT ratio. He has completed 67.7 percent of his passes, averaging 7.7 YPA. Love's top receiving target this season is WR Romeo Doubs (41 receptions for 522 yards and four TDs), who has taken the lead following TE Tucker Kraft's season-ending injury. Jacobs, who is questionable for Thursday's game, paces the Packers' ground game with 169 carries for 648 yards and 11 touchdowns.

Green Bay scores 23.9 points per game (13th) and averages 338.9 total yards (13th), including 222.5 passing yards (14th) and 116.5 rushing yards (15th). The Packers' defense surrenders 18.4 points (5th) and 278.7 total yards (4th) per game, including 182.3 passing yards (5th) and 96.5 rushing yards (6th).

Green Bay Packers Injury Report:

• LB Quay Walker, RB Josh Jacobs, LB Edgerrin Cooper, S Javon Bullard, CB Keisean Nixon, WR Jayden Reed, WR Matthew Golden, DE Karl Brooks, CB Nate Hobbs, and WR Dontayvion Wicks are questionable.

Lions snatched victory from the jaws of defeat on Sunday

Detroit (7-4 SU, 6-5 ATS, and 6-5 O/U) defeated the New York Giants 34-27 in overtime on Sunday, bouncing back from a loss at Philadelphia the previous week.

The Lions won but failed to cover as 14-point favorites over the G-Men, as the visitors took an early lead and never relented, taking a 10-point lead early in the fourth quarter. Detroit responded by scoring three times on its final four drives to steal the win. New York dominated the time of possession, but was 1-for-3 on fourth down and 1-for-3 in the red zone. The visitors passed for nearly 400 yards, while the home team rushed for nearly 250.

“That very easily — a number of times — could’ve gone the other way, but it didn’t,” Lions coach Dan Campbell said. “We made the plays we had to make.”

QB Jared Goff leads the Detroit offense with 2,769 passing yards, 23 touchdowns, and five interceptions. He has completed 69.3 percent of his passes, averaging 7.9 yards per attempt. Goff's top receiving targets are WR Amon-Ra St. Brown (75 receptions for 884 yards and nine TDs) and WR Jameson Williams (31 receptions for 562 yards and five TDs). RBs Jahmyr Gibbs (155 carries for 951 yards and ten TDs) and David Montgomery (115 carries for 511 yards and five TDs) pace the Lions' run game.

Detroit scores 29.6 points per game (2nd) and averages 378.5 total yards (4th), including 238.6 passing yards (8th) and 139.8 rushing yards (3rd). The Lions' defense surrenders 22.1 points (12th) and 312.3 total yards (10th) per game, including 210.5 passing yards (15th) and 101.7 rushing yards (11th).

Detroit Lions Injury Report:

• OT Taylor Decker, OT Penei Sewell, C Graham Glasnow, S Brian Branch, S Kerby Joseph, CB Terrion Arnold, and WR Kalif Raymond are questionable.

Packers vs. Lions Pick and Preview

Spread Pick for Packers vs. Lions

• Detroit -2.5 (4 Units)

The Packers have momentum, while the Lions looked shaky at times on Sunday, but I still lean towards the home team's side ATS on Turkey Day. Green Bay easily handled Detroit in Week 1, but the visitors haven't looked nearly as dominant since then. The Lions' offense is more reliable right now, in my opinion, especially with Green Bay dealing with injuries to several skill position players. Even with less involvement from Montgomery, the ground game has been humming, with Gibbs coming off a huge game against the Giants. I expect both backs to get significant touches in the red zone on Thursday. The Packers' defense looked dominant on Sunday, but I question how much of that was McCarthy's fault.

Bet on Detroit to cover the 2.5-point spread.

Over/Under Pick for Packers vs. Lions

• Under 49.5 (5 Units)

I anticipate a run-heavy game plan by both teams. Gibbs rushed for 219 last game and ranks third in the NFL in rushing yards this season. While I expect he'll get a steady diet of handoffs, the Packers held him to 19 rushing yards earlier this season. Montgomery was also held in check in that game (25 rushing yards). I expect Green Bay to lean on its defense and run game, as it did on Sunday against Minnesota.

Both teams have been unreliable recently, losing games they shouldn't. That makes it a gamble to expect either team to play flawlessly, especially on limited rest. There are significant injury concerns on both sidelines, as well. I'll take the under in this divisional rivalry matchup.