Pittsburgh Steelers vs. Los Angeles Chargers, Preview, Odds, Picks and Prediction for Sunday, November 9th, 2025

By: Adam Rauzino Published 11/07/2025, 06:05 PM ET
Pittsburgh Steelers vs. Los Angeles Chargers prediction.
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We've go an AFC matchup of superstar head coaches in this Steelers vs. Chargers prediction. The Pittsburgh Steelers (5-3, 4-4 ATS, 5-3 O/U) take on the Los Angeles Chargers (6-3, 3-5-1 ATS, 5-4 O/U) in an inter-conference showdown on Sunday afternoon, and we have everything you need to know and the prediction. The Steelers posted a home win against the Colts last week. The Chargers netted a road win against the Titans. The Steelers earned a 20-10 home win against the Chargers last season.

Can the Chargers record a third straight win on Sunday afternoon? Check out the Steelers vs. Chargers prediction. Do you need a boost in your handicapping? Try our NFL Betting Picks!

Steelers vs. Chargers Matchup

Steelers Rebound in Win vs. Colts

The Pittsburgh Steelers are targeting a second straight win. Pittsburgh is in great shape in the standings, leading the division, two games ahead of the Ravens. The Steelers are 3-2 in their past five games. They were dealt a road loss by the Bengals last month and concluded October with a 35-25 home loss against the Packers. Next, Pittsburgh answered with a big 27-20 home win against a potent Colts team last week. They were three-point dogs in the win. The Steelers have covered in one of three road games.

Aaron Rodgers has been steady. The future Hall of Famer has posted 219 or more yards in three of his past five games. He has connected on 69% of his passes. Rodgers amassed 203 yards last week and has recorded 1692 passing yards, accompanied by a 17:5 TD to INT ratio. Jaylen Warren did not have any success last week, managing 33 yards. The 27-year-old running back has surpassed 50 yards in three games and has amassed 404 yards.

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Pittsburgh has a strong receiving group. DK Metcalf was quiet last week, but has been consistent in most games and has brought in 467 receiving yards this season. Calvin Austin III had 56 yards last week and 223 yards on the year. The Pittsburgh offense had one of its worst outputs of the season last week, recording only 225 total yards. They are only averaging 288 yards per game.

The Steelers' defense rebounded from a few bad performances with a stellar outing last week, keeping a good Indianapolis offense to 365 yards and only 2.9 yards per rush. The Steelers are conceding 383 yards per game. Linebacker Payton Wilson leads the team with 71 tackles. The pass defense is pegged 32nd, while the rush defense is strong, coming in at 15th.

Pittsburgh is averaging 25.3 points on the season, ranking them 12th. The Steelers are conceding an average of 24.4 points, placing them 21st.

Chargers Seek Third Straight Win

The Los Angeles Chargers are seeking a third straight win. Los Angeles is one game behind the Broncos atop the division. The Chargers are 3-2 in their past five games. This includes an ugly loss against the Colts. They earned a 37-10 home win against the Vikings two weeks ago and managed a 27-20 road win against the Titans last week in a meeting that had the Chargers marked as the big 10-point favorites. The Chargers have covered the spread in just one of their past six games.

Justin Herbert had one of his better games of the season last week, netting 255 passing yards. The 27-year-old QB has reached 250 yards on five occasions this season and has delivered 2390 passing yards, accompanied by an 18:8 TD to INT ratio. The Chargers do not run a ton. Omarion Hampton leads the squad with 314 rushing yards, but remains on the IR with a foot injury. Kimani Vidal is seeing an increase in action due to his injury. The 24-year-old RB has 309 rushing yards.

The receiving group is stacked. They have three receivers with at least 450 yards. Keenan Allen has 520 yards. Ladd McConkey has registered 50 or more yards in five games this season and leads the squad with 524 yards on the year. The Los Angeles offense issued 343 total yards last week. This is well below its season average of 375 yards per game.

The Chargers' defense is above average. They have been hit or miss at times, but have only conceded 20 points in their last two games. They kept Tennessee to 206 yards last week, improving their season average to only 286 yards per game. Derwin James Jr. is one of the best safeties in the NFL. He has made 57 tackles.  The pass defense is rated third, while the rush defense is not as stingy, coming in at 16th.

Los Angeles is averaging 23.9 points on the year, ranking them 16th. The Chargers are holding opponents to 21.4 points, placing them 12th in the NFL.

Key Injuries and Analysis:

Pittsburgh:

Questionable

  • LB Alex Highsmith (ankle) was limited in practice
  • S Jabril Peppers (quad) was limited in practice
  • S DeShone Elliott (knee) was a starter and placed on the IR.

LA Chargers

Questionable

  • S Tony Jefferson (hamstring) was limited in practice.
  • G Mekhi Becton (knee) is questionable.
  • Star LT Joe Alt (ankle) re-injured his ankle and was placed on the IR.

Steelers vs. Chargers Pick

Spread Pick for Steelers vs. Chargers

  • Los Angeles Chargers -3 (5 units)

The Pittsburgh Steelers have been inconsistent. They have dropped two of their past three games, including a loss to the Bengals in their previous road game. While Pittsburgh beat the Colts last week, the offense was kept in check, managing only 225 total yards.  The Los Angeles Chargers are in a groove. They have won two straight clashes and stand at 3-1 in their past four games.

Furthermore, Los Angeles passes more than most teams, passing in just over 60% of its plays. This is good news for Herbert against a weak pass defense. The Steelers are conceding an average of 278 passing yards per game, pegging them last in the NFL. Also, Pittsburgh passes more than it runs by a huge margin. This is ideal for the Chargers. They have a stingy secondary that is keeping opponents to only 177 passing yards per game, placing them 3rd in the NFL.

Over/Under Pick for Steelers vs. Chargers

  • Over 45 (5 units)

I expect a barrage of scoring. Pittsburgh is netting big numbers. They have scored 25 or more points in three of their past four games. The Chargers' defense has endured its fair share of shaky performances this season. They gave up 27+ points against the Commanders, Dolphins, and Colts.

In addition, Los Angeles has a dangerous offense that ranks 5th in the NFL in total yards and sixth in passing yards. They have a quick offense, ranking 2nd with 66 plays per game. The Steelers' defense does not stand out in any area. The Steelers have surrendered 30 or more points in two of their past three road games. The over is a convincing 4-1 in the Chargers' past five games.

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