Seahawks vs. Rams Preview, Odds, Preview, Picks, and Prediction for Sunday, November 16, 2025
Use Code WWWC On Sunday, the Seattle Seahawks will face the Los Angeles Rams at SoFi Stadium in Week 11 NFL action, pitting the NFC West division leaders and dueling NFL MVP candidates, QBs Sam Darnold and Matthew Stafford. This is a rivalry battle with bragging rights on the line, and we have you ready to go with our Seahawks vs. Rams prediction, preview, and picks.
Kickoff from Inglewood, CA, is at 4:05 p.m. ET. The Rams are three-point spread favorites, and the game total is 48.5 points scored.
This is the first game of the season between the Seahawks and Rams, with the teams scheduled to play again on December 18 in Seattle. Sunday's Seahawks vs. Rams matchup is historic, as it's the first time in the Wild Card era (since 1990) that teams with both a winning percentage straight-up and against the spread of 77+% are facing each other in their tenth game or later. These division rivals split their two games last season, with each team winning on the road. LA leads the series 6-4 straight-up and 8-2 against the spread in the previous ten meetings. The under went 7-3. If you want the Seattle Seahawks vs. LA Rams prediction, read on and check out our NFL Picks to beat the sportsbooks!
Seattle Seahawks vs. LA Rams Matchup
Seahawks are coming off a dominant performance
Seattle (7-2 SU, 7-2 ATS, and 6-3 O/U) beat Arizona 44-22 last weekend, covering as 7.5-point spread favorites. The Seahawks have won and covered in four straight.
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Seattle is coming off its ninth-straight win over Arizona, a game it dominated on both sides of the field. Darnold averaged 13.4 yards per pass, and the Seahawks' ground game produced 198 yards, while DE DeMarcus Lawrence returned two fumbles for touchdowns. Seattle scored on its first drive and never looked back, building momentum ahead of a divisional showdown with Los Angeles.
“We had guys step up, and nobody flinched,” Seahawks head coach Mike Macdonald said. “And it took all 70 again. That’s how we roll.”
Darnold paces the Seattle offense with 2,262 passing yards (251.3 per game) with 17 touchdowns and six interceptions. He has completed 71.1 percent of his passes. The USC product's top receiving targets are WRs Jaxon Smith-Njigba (63 receptions for 1,041 yards and five TDs) and Cooper Kupp (26 receptions for 367 yards and one score). Michigan State product Kenneth Walker III leads the Seahawks on the ground with 120 carries for 539 yards and three touchdowns.
Seattle scores 30.6 points per game (3rd) and averages 360.4 total yards (10th), including 24.1 passing yards (7th) and 114.3 rushing yards (17th). The Seahawks defense surrenders 19.1 points (5th) and 307.3 total yards (8th) per game, including 216.7 passing yards (18th) and 90.7 rushing yards (2nd).
Los Angeles is building momentum for a deep playoff run
Los Angeles (7-2 SU, 7-2 ATS, and 4-4-1 O/U) beat San Francisco 42-26 as six-point spread favorites last Sunday. The Rams have won and covered in four straight.
LA made a statement on the road in Santa Clara, jumping on the 49ers from the start and finishing strong with two fourth-quarter touchdowns. Stafford passed for four touchdowns, and RB Kyren Williams added two rushing scores. San Francisco coughed up the football twice and committed seven penalties, while the Rams were turnover and penalty-free. LA was also a combined 6-for-10 on its third and fourth downs, while the home team was 4-for-11.
“I think our team has a bunch of mental toughness, resilience, and the ability to be able to respond,” Rams coach Sean McVay said. “They stay connected through the good and through the challenging moments. I love this group. I’m excited about being able to build with them as we continue on this second half of the season.”
Stafford leads Los Angeles into action with 2,427 passing yards (67.1% CMP%), 25 touchdowns, and two picks. He averages 7.8 yards per pass and 269.7 yards per game. The Georgia product's top receiving targets are WR Puka Nacua (66 receptions for 775 yards and four TDs) and WR Davante Adams (42 receptions for 568 yards and nine TDs). The Rams' run game is paced by fourth-year pro Williams (146 carries for 659 yards and five scores).
LA scores 27.9 points per game (5th) and averages 373.3 total yards (6th), including 259.9 passing yards (3rd) and 113.4 rushing yards (18th). The Rams' defense allows 17.0 points (2nd) and 312.9 total yards (10th) per game, including 216.0 passing yards (17th) and 96.9 rushing yards (9th).
Key Injuries and Analysis for Seahawks vs. Rams
Seattle Seahawks Football Injury Report:
- C Jalen Sundell (knee) is questionable to play.
- WR Tory Horton (groin/shin) is questionable to play.
- LB Ernest Jones IV (knee) is questionable to play.
- OG Grey Zabel (heel) is questionable to play.
Los Angeles Rams Football Injury Report:
- WR Davante Adams (oblique) is expected to play.
- DE Kobie Turner (back) is questionable to play.
Seahawks vs. Rams Pick and Preview
Moneyline Pick for Seahawks vs. Rams
- Seattle ML (5 Units)
I don't read much into the -3 spread, as anything higher would encourage a lot of bets on Seattle, and anything lower would have bettors flocking to Los Angeles' side. That said, the line is also short because this is a matchup between talented, evenly-matched teams. While I initially considered taking the points with the visitors, I'm inclined to bet on them to win straight-up at plus odds.
Seattle is 11-1 straight-up on the road under Macdonald, with five straight wins as underdogs. That's an encouraging stat, but it's hardly the only one. The Seahawks have started games hot, as well. They're 7-2 ATS in the first half of their games this season, as Darnold has been red-hot out of the gate (12 TDs to 2 INTs with a 75% completion percentage and 11.1 Yards per Attempt). He has the passing game humming, and the Hawks' run game has also been effective with Walker and Zach Charbonnet.
I'm also skeptical of Los Angeles, as it has cleaned up in recent weeks against a string of backup QBs. Not all four-game winning streaks are alike. The Rams also have a significant challenge on their hands blocking the Seahawks' pass rushers. Seattle blitzes at the second-lowest rate in the NFL (19.1%), yet boasts the second-most sacks and the third-highest pressure rate (40.4%). The 37-year-old Stafford doesn't move like a spring chicken, either. I expect the visitors to create havoc with just a four-man rush, which is an x-factor. The Rams' QB has carved up opposing defenses when blitzed (20 TDs and 0 INTs), but he's much less effective when facing traditional rushes (5 TDs and 2 INTs).
Over/Under Pick for Seahawks vs. Rams
- Under 48.5 (4 Units)
Betting Trends: The under is 4-1 in the Rams' last five home games, with the lone over coming in an overtime game against San Francisco. Seattle has allowed 20 or fewer points in seven of nine games, as well.
In a divisional matchup between the league's top two defenses in DVOA, I lean towards the under. Los Angeles is without WR Tutu Atwell (IR), and Adams and Jordan Whittington missed practice time with injuries this week, affecting their pass-catching depth. That's significant, as Stafford will need all the help he can get against the Seahawks' fearsome pass rush. The vet averages 2.75 seconds per dropback, which ranks 14th in the NFL, and could be sped up more on Sunday.
Los Angeles' pass rush (27 sacks) will also be Seattle's biggest test of the season. The Rams are also stout against the run, as DT Poona Ford and company have done an excellent job limiting explosive runs. LA is among the league leaders in takeaways (14), thanks to DC Chris Shula's complex defensive philosophy, which confuses opposing offenses. Safety Quentin Lake can play all over the field and will be tasked with defending Smith-Njigba between the numbers and Kupp out of the slot. His impact will be felt early and often.
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