Buffalo Sabres at Detroit Red Wings Prediction and Picks, Saturday, November 15, 2025

By: David Delano Published 11/15/2025, 01:18 AM ET
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The Detroit Red Wings will (10-7-0) host the Buffalo Sabres (5-8-4) on Saturday night. The Sabres beat the Red Wings 4-2 in Buffalo on Oct. 22.

If you are looking for help with your NHL picks, keep reading our full Sabres vs Red Wings prediction, along with our expert picks.

Sabres are struggling

The Sabres head into Detroit struggling, with losses in five straight and nine of their last 10. On Thursday, Buffalo fell 6-3 to the Colorado Avalanche.

Buffaloโ€™s issues are extensive. The Sabres rank 29th in both goals scored and goals allowed per game, 31st in shots allowed, and 30th in shooting percentage. The Sabres have used three different goaltenders this season, with Alex Lyon getting most of the work. Lyon is 3-5-3 with a 3.07 goals-against average and .905 saves percentage.

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Will this be the season?

The Red Wings snapped a three-game losing streak with a 6-3 home win over the Anaheim Ducks on Thursday. No wins can be taken for granted for the Detroit Red Wings who are a historic franchise with 11 Stanley Cup titles, but they are now in the midst of a nine-year postseason drought, tied for the third-longest in NHL history.

Detroit has split its goaltending workload fairly evenly. John Gibson is 4-5-0 this season with a 3.14 goals-against average and .882 save percentage, while Cam Talbot is 6-2-0 with a 2.93 goals-against average and .892 save percentage.

Buffalo Sabres vs. Detroit Red Wings Predictions

Money Line Pick for Sabres vs. Red Wings:

  • Red Wings -1.5 (+145) 2 units and 2 units Red Wings -158

Every losing streak eventually ends in the NHL, but I donโ€™t see Buffaloโ€™s ending here. The Sabres have been terrible recently, with their last four losses all coming by at least three goals. They have also dropped their last three games in Detroit.

The Red Wings have won nine of their last 11 games when playing on one day of rest, and they are going up against a Sabres team that is winless on the road so far, Detroit is the only side I can take. I think this is a good spot for a half moneyline, half puckline play with the Red Wings.

Total Play Sabres vs. Red Wings:

  • Over 6.5 (4 units)

Buffalo has allowed at least five goals in each of its last three road games and has seen at least seven total goals scored in its last five road outings overall.

Detroit has produced big numbers in certain moments home, including the six goals they scored on Thursday against Anaheim. In the end, the Red Wings have also given up their fair share of goals this season.

I wouldnโ€™t be surprised to see this land around eight goals. Iโ€™m taking the over.

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