Buffalo Sabres at Ottawa Senators Predictions, Picks, Odds, and Line Movement for December 23

By: Kyle Kargel Published 12/23/2025, 08:50 AM ET
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Buffalo Sabres vs Ottawa Senators picks take center stage in this Atlantic Division matchup as Buffalo heads north of the border to face Ottawa on Tuesday night, and bettors digging into NHL predictions will find a game shaped by momentum, injuries, and a clear home-ice lean in the market.

Quick Picks and Prediction

  • Spread Pick: Ottawa Senators -1.5
  • Total Pick: Over 6
  • Projected Final Score: Senators 5, Sabres 2

Odds and Line Movement

Opening Odds

Team Moneyline
Buffalo Sabres +140
Ottawa Senators -170
Total Over Under
6 +114 -140

Current Odds

Team Moneyline
Buffalo Sabres +140
Ottawa Senators -170
Total Over Under
6 +114 -140

Line Movement - Puck Line

Date Favorite Underdog
12/22 OTT -1.5 BUF +1.5

Line Movement - Total

Date Over Under
12/22 6 6

Key Matchups and Handicap

Ottawa enters this matchup with momentum after a high-scoring win over Chicago, showing its ability to push the pace late and finish games with offensive pressure. Tim Stutzle and Brady Tkachuk continue to drive the Senators’ attack, and Ottawa’s willingness to trade chances has translated well at home. The Senators’ offensive surge puts pressure on a Buffalo team that is already dealing with notable defensive absences.

Buffalo, however, is not coming in cold. The Sabres have strung together multiple wins, including a convincing victory over New Jersey, showing balanced scoring throughout the lineup. That said, injuries on the blue line have thinned Buffalo’s margin for error. Without Conor Timmins, the Sabres’ defensive depth takes a hit, and that becomes magnified against an Ottawa team that thrives when games open up.

From a betting perspective, Ottawa’s home ice and offensive momentum outweigh Buffalo’s recent form. With both teams capable of scoring and defensive issues present for the Sabres, this sets up as a game where Ottawa can win by a narrow margin while still pushing the total upward.

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  • Ottawa has been favored in recent home matchups following high-scoring wins.
  • Buffalo has continued to win games despite missing key defensive pieces.
  • Ottawa games have trended toward higher-scoring outcomes when the Senators dictate pace.

Key Injuries and Notes (BUF and OTT)

  • Buffalo defenseman Conor Timmins is out with a broken leg.
  • Buffalo has dealt with multiple lineup disruptions throughout the season.
  • Ottawa enters with most core contributors available.

ATS and Total Picks

  • Against the Spread: Ottawa Senators -1.5
  • Total: Over 6

Final Score Prediction

This shapes up as a competitive divisional game where home ice and offensive depth matter late.

Ottawa Senators 5, Buffalo Sabres 2

How to Bet

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