Buffalo Sabres vs Anaheim Ducks Picks and Predictions for Sunday March 22 2026

By: Kim Smith Published 03/22/2026, 05:15 AM ET
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The Buffalo Sabres head west to take on the Anaheim Ducks at the Honda Center with puck drop scheduled for 8:00 PM on ESPN+. Anaheim enters this matchup as the home favorite at -130 on the moneyline, while Buffalo is listed at +110. The total for this contest is set at 6.5 goals, and the puck line shows Buffalo +1.5 (-218) and Anaheim -1.5 (+180). Be sure to check out our free NHL picks for more daily insights and expert selections.

Buffalo’s Momentum Faces a Tough Road Test

The Sabres come into this game with a strong 43-20-6 record, including a solid 21-11-3 mark on the road. Over their last five games, Buffalo has recently won over San Jose twice, Vegas, and Toronto, while suffering a loss to Washington. This team has been playing excellent hockey lately and enters this matchup with plenty of confidence.

Buffalo averages 3.45 goals per game while allowing 2.90 goals against, showing a well-balanced offensive and defensive approach. They generate 27.9 shots per game and allow 29.4 shots against, which suggests they are comfortable playing in higher-event games where scoring opportunities go both ways.

One of Buffalo’s biggest strengths is their special teams play, particularly their penalty kill, which sits at 83.3%. They have also scored 10 short-handed goals this season, highlighting their ability to create offense even when down a man. Their power play converts at 20.3%, making them dangerous in multiple situations. If Buffalo can continue their strong recent form, they have a great chance to succeed on the road.

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Anaheim Aims to Defend Home Ice

The Ducks enter this contest with a 38-27-4 record and have been strong at home with a 22-10-2 mark. Over their last five games, Anaheim has recently won over Utah and Montreal, while losing to Philadelphia, Ottawa, and Toronto. This team has shown flashes of offensive firepower but has struggled with consistency.

Anaheim averages 3.20 goals per game but allows 3.44 goals against, which points to defensive issues. They generate 30.2 shots per game and allow 29.0, indicating a fast-paced style that can lead to high-scoring games. However, their defensive play and penalty issues have often put them in difficult situations.

Special teams have been a weakness for Anaheim. Their power play converts at just 16.8%, while their penalty kill sits at 78.3% and has allowed 49 power play goals. This could be a key factor against a Buffalo team that can capitalize on opportunities.

Anaheim’s strength lies in their ability to push the pace offensively, especially at home. If they can clean up their defensive mistakes and stay out of the penalty box, they can be competitive in this matchup.

Buffalo Sabres vs Anaheim Ducks Pick

Sabres vs Ducks Pick

  • Pick: Buffalo Sabres +110

Buffalo comes into this game as the hotter and more consistent team, especially over their last five games. Their balanced offensive attack and stronger defensive numbers give them an edge, even on the road. I like Buffalo to continue their momentum and pull off the upset here.

Sabres vs Ducks Total Pick

  • Pick: Over 6.5

I’m going with the over in this matchup because both teams play at a high pace and have shown defensive vulnerabilities. Anaheim, in particular, allows a high number of goals, and Buffalo has been scoring consistently. I expect plenty of chances on both sides, leading this game over the total.

Final Score Prediction: Buffalo Sabres 4, Anaheim Ducks 3

This prediction was written before the completion of game play on Saturday.

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