Colorado Avalanche vs. Buffalo Sabres, Picks and Prediction, Monday, October 13, 2025

By: Mike Fink Published 10/13/2025, 02:20 AM ET
Colorado Avalanche vs Buffalo Sabres prediction
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The Colorado Avalanche face the Buffalo Sabres with both teams heading in opposite directions to start this season. The Avalanche won their first two games and have earned points in all three games on the season thus far. The Sabres have lost their first two games and are eager to get a win on their home ice. Who will win this matchup? Check out our Avalanche vs Sabres prediction!

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Colorado has stepped up across the board

The Avalanche are off to a hot start with their offense leading the way, scoring 10 goals in their first three games, with four goals in their recent game. Nathan MacKinnon and Martin Necas have scored five goals and seven assists to lead the top line, but the rest of the offense has stepped up as well. Artturi Lehkonen and Victor Olofsson have combined for two goals and three assists, while defenseman Cale Makar has added three assists from the point to open up the offense.

The offense has been great, but the defense has also stepped up, allowing only seven goals in their first three games. Cale Makar and Devon Toews have anchored the top pairing, while Brent Burns and Sam Malinski have added depth to the lineup, creating turnovers in the defensive zone while limiting shots on the net. In addition, goaltender Scott Wedgewood has looked great early on with a .925 save percentage and a 1.95 goals-against average on 80 shots.

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Sabres have struggled on both ends of the ice

The Sabres are off to an awful start with their offense letting them down and scoring only one goal in their first two games. The hope is that Tage Thompson and defenseman Rasmus Dahlin get going, as they are the two best players on the team and scored 61 goals last season but have yet to record a point this season.

The offense has struggled, but the defense has also disappointed, allowing seven goals in two games. Rasmus Dahlin and Owen Power have led the top two pairings but the rest of the group has been a mess, allowing open shots on the net at will. The one bright spot is the play of goaltender Alex Lyon, who has stopped 57 of 62 shots he’s faced.

Avalanche vs Sabres Pick

Money Line Pick for Avalanche vs. Sabres

  • Avalanche (-155) (4 units)

The Avalanche are off to a remarkable start and I see them taking over this game from the first period. The Avalanche, who have scored 10 goals in three games, should find the back of the net at will with Nathan MacKinnon, Martin Necas, and the rest of the forward unit carrying the puck into the offensive zone while creating open shots with quick passes. The Avalanche, who have allowed only seven goals in three games, should limit the Sabres offense, which has only scored one goal in their first two games, with Cale Makar, Devon Toews, and the rest of the defensive unit creating turnovers in the defensive zone while limiting shots on the net, allowing goaltender Scott Wedgewood to make plenty of big saves. The Avalanche should win the game in a dominant performance on the road.

Take the Avalanche money line as road Favorites.

Over/Under Pick For Avalanche vs Sabres

  • Over 6.5 (5 Units)

The Sabres have looked hapless on the offensive end but the Avalanche are led by their offense and I see this game being a high-scoring one from the opening puck drop. The Sabres should create plenty of scoring chances with Tage Thompson and Rasmus Dahlin stepping up and firing good shots on the net. The Avalanche look to build off a four-goal game and run up the score against the Sabres, who have allowed seven goals in their first two games, with Nathan MacKinnon, Martin Necas, Victor Olofsson, and the rest of the forward unit crashing the net on the rush and creating open shots with effective puck movement while Cale Makar picks apart the Sabres defense from the point. The Over should cover in a low-scoring game with both offenses stepping up.

Take the Over on 6.5 goals.

The Avalanche head to Buffalo to face the Sabres who are on the ropes after a slow start.

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