Detroit Red Wings vs St. Louis Blues Picks, Prediction, Odds, and Line Movement for Tuesday November 10 2026

Detroit and St. Louis both enter Tuesday with three straight losses. Their October 31 meeting was a 5-4 Blues win, but a repeat of that free-flowing game looks less likely with Dylan Larkin unavailable. Detroit has to rebuild its center matchups on the road, and that gives St. Louis a specific place to attack rather than simply hoping its own skid ends at home.

The Red Wings do get John Gibson back in goal, along with forwards Marco Kasper and Mason Appleton. Those returns help. Losing Larkin to suspension, however, removes a player Detroit trusts to take demanding faceoffs and match up against top competition. St. Louis has not looked convincing lately, but it can choose when to deploy Robert Thomas against those makeshift lines at Enterprise Center.

Puck drop is 8 p.m. ET. The Blues have gone 4-2-1 at home and Detroit 3-3-2 away. St. Louis comes off a 3-1 defeat to Nashville in which long stretches passed without sustained pressure. Being at home does not fix that automatically. It does let the Blues dictate more of the forward matchups, and Thomas is the player most likely to take advantage.

Detroit is averaging around 2.61 goals per game, St. Louis about 2.94. Those numbers help explain the split between posted totals of 5.5 and six. Both clubs have had trouble manufacturing offense once their first look breaks down. That makes an extra power play, a faceoff in the offensive end or one misplayed rebound especially consequential.

Caesars showed St. Louis -141 in a November 10 odds comparison, with DraftKings -142 and BetMGM -145. Detroit was available at roughly +118 to +128 depending on the book. The range matters: at -141 the Blues are playable, while a move much beyond -145 asks for more certainty than their recent results deserve.

There is a real difference between laying -141 on the Blues and guessing whether the clubs combine for six goals. Some books show 5.5, others six, and either total can be decided by one late empty-net attempt. The full-game St. Louis moneyline cashes on a win of any kind. The uncomfortable part is obvious: this favorite has lost three straight too.

Detroit will rely more heavily on Alex DeBrincat, Lucas Raymond and the supporting forwards without Larkin. DeBrincat is projected alongside Emmitt Finnie and Viktor Arvidsson, while Andrew Copp centers another line with Raymond. The return of Marco Kasper and Mason Appleton increases the available options, but there is no instant replacement for Larkin's two-way minutes and faceoff work.

Gibson is confirmed back after two games out with a lower-body injury. His early save percentage, near .860, will attract attention, but Detroit's coverage of rebounds matters just as much. Moritz Seider will likely see the busiest defensive minutes. A penalty kill around 69 percent cannot keep granting the Blues clean chances, especially with Larkin unavailable for key defensive draws.

Robert Thomas remains the most important playmaker in St. Louis's projected top six, skating with Dylan Holloway and Jimmy Snuggerud. Jake Neighbours and Mason McTavish create another line capable of attacking Detroit's defense below the dots. The Blues will also regain Logan Mailloux for his season debut after the defenseman recovered from a broken right hand.

Hofer is first on St. Louis's projected goalie list, not yet a confirmed starter. His early .919 save percentage and 2.36 goals-against average are promising if he gets the assignment. The Blues also have an approximately 84.4 percent penalty kill. That would let St. Louis spend more of the night at even strength instead of chasing Detroit after a careless penalty.

Detroit's struggling penalty kill makes a Thomas-led power play unusually important here. St. Louis has scored on about 22.4 percent of its advantages, and one clean setup for Snuggerud or a shot from the point may be the scoring separation it needs. Detroit must stay disciplined and win enough draws to keep those chances from becoming long possessions.

The risk is that St. Louis has lost its last three and looked flat in long stretches against Nashville. Detroit could exploit careless defensive-zone changes or a slow Blues start. Still, the combination of home ice, Hofer's early performance and Detroit's missing center offers a clearer argument for the favorite than either team's overall win-loss record alone.

This is not a ringing endorsement of the Blues' recent play. A three-game skid should keep bettors from paying an inflated favorite price. But Detroit is missing the center it leans on for difficult matchups, and the St. Louis power play gets a vulnerable penalty kill. I expect the Blues to find enough control at home to edge this one without covering a larger handicap.

Best Bet: St. Louis Blues moneyline -141 at Caesars, playable at -145 or better. Hofer's steadiness and the Blues' special-teams opportunity are the deciding factors in a close contest. Prediction: St. Louis Blues 3, Detroit Red Wings 2. The low margin reflects both teams' difficulty sustaining offense lately.