Florida Panthers vs. Buffalo Sabres, Picks and Prediction, Saturday, October 18, 2025

By: Bosun Akinpelu Published 10/18/2025, 04:31 AM ET
Panthers vs. Sabres prediction
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Florida (3-3-0) will be trying to snap its three-game losing streak when they visit KeyBank Arena on Saturday afternoon to face Buffalo (1-3-0) at 1 PM. ET. Read on to find out which team picks up the win in this Panthers vs. Sabres prediction. Looking to win big this hockey season? We have the best NHL Picks to help you out!

The Panthers are coming off a 3-1 loss to New Jersey. The Sabres are coming off an 8-1 win over Ottawa.

Florida is 8-2-0 in its last 10 games against Buffalo.

Florida Looking For First Road Win

The Panthers kicked off their title defense with three straight wins. They have struggled on their first road trip of the season, dropping their first three games, and will try to pick up their first road win of the season when they play on Saturday.

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Florida averages 2.50 goals per game. They scored one goal on 22 shots in their last game.

Brad Marchand leads Florida with six points from three goals and three assists. Anton Lundell has five points from two goals and three assists, while Evan Rodrigues has four points from two goals and two assists.

Florida is giving up 2.83 goals per game, which is 12th in the league. They’ve killed 90 percent of their penalties, which is seventh.

Daniil Tarasov saved 30 of the 33 shots that he faced. He is 0-2-0 with a 3.08 GAA and a .887 save percentage.

Buffalo Going For Second Consecutive Win

The Sabres snapped their three-game losing streak with a win over Ottawa in their last game, giving them their first win of the season. They will try to keep the momentum going and pick up their second straight win when they play on Saturday.

Buffalo averages 2.50 goals per game. They scored eight goals on 27 shots in their last game.

Zach Benson leads Buffalo with four points from four assists. Alex Tuch has three points from one goal and two assists, while Josh Doan has three points from three assists.

Buffalo is giving up 3.50 goals per game, which is 22nd in the league. They’ve killed 93.8 percent of their penalties, which is third.

Alex Lyon saved 33 of the 37 shots that he faced. He is 1-3-0 with a 3.05 GAA and a .911 save percentage.

Panthers vs. Sabres Picks

Money Line Pick for Panthers vs Sabres

  • Florida Panthers ML (4 Units)

The Panthers split their first six games, while the Sabres have lost three of their four games. Florida has the edge here because they’ve done a better job on the offensive end, scoring 10 goals in their last four games. They’ve also played well on special teams, converting over 25 percent of their power play opportunities. The Sabres have done a good job of killing penalties, but they’ve struggled defensively, giving up three or more goals in four straight games, so expect them to have a hard time slowing down the Panthers.

Buffalo will have a hard time keeping up in this game because they’re not very good offensively, scoring two goals through their first three games before going off on Ottawa in their last game. They’ve done a better job on special teams, converting over 21 percent of their power play opportunities. The Panthers are one of the best teams in the league when it comes to penalty kills, and they’ve been solid defensively, keeping opponents under three goals per game, so expect them to keep Buffalo’s offense in check. Take Florida on the money line.

Over/Under Pick for Panthers vs. Sabres

  • Under (4 Units)

The Panthers played under the total in their last two games, while the Sabres played under the total in three of their last four games. Florida averages 2.50 goals per game. They averaged 2.33 goals per game in their last three road games and converted eight percent of their power play chances during that span. They are facing a team that has killed 92 percent of their penalties in their last three games and given up 10 goals in their last three games. The Sabres average 2.50 goals per game. They averaged 3.33 goals per game in their last three games and converted 33 percent of their power play chances. They are facing a team that killed 85 percent of their penalties in their last three games and is giving up 2.83 goals per game. Don’t expect these teams to score enough goals to push the score over the total. The Panthers and Sabres played under the total in eight of their last 10 meetings.

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