Texas Rangers vs. Houston Astros, Picks and Prediction, Monday, September 15, 2025

By: Bosun Akinpelu Published 09/15/2025, 11:00 AM ET
Rangers vs. Astros prediction
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Texas (79-70) will be trying to keep its AL West title hopes alive when they visit Daiken Park on Monday night to face Houston (81-68) in the first game of its three-game series at 7:40 PM. ET. Read on to find out which team picks up the win in this Rangers vs. Astros prediction. Need some winners this baseball season? Check out our Free MLB Picks.

Jack Leiter, 9-8, 3.81 ERA, will get the start for the Rangers. The Astros will counter with Jason Alexander, 4-1, 4.19 ERA.

Texas is 6-4 in its last 10 games against Houston.

**This preview was written before Sunday’s games were played.**

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Texas Going For Series Lead

The Rangers bounced back from their series loss to Arizona with series wins over Houston, Milwaukee, and the Mets. They are third in the AL West standings, two games behind Houston and Seattle, who are tied for the division lead. They will try to keep the momentum going and move within one game of the division lead with a win on Monday.

Texas averages 4.30 runs per game, which is 18th in the league. Their .237 batting average is 26th in the league. Their .306 on base percentage is 24th, while their .388 slugging percentage is 26th.

Josh Smith leads Texas with a .259 batting average. Corey Seager leads the team with 21 home runs, while Adolis Garcia leads the team with 73 RBI.

Texas is giving up 3.65 runs per game, which leads the league. Opponents have a .228 batting average against the Rangers, which is second in the league. Their 3.41 ERA leads the league, as does their 1.17 WHIP.

In his last start, Leiter gave up seven hits and three runs in 4.2 innings, leading to a 5-4 win over Milwaukee. He gave up six runs in two starts against Houston this season.

Houston Trying To Take Division Lead

The Astros bounced back from their series loss to Toronto with a series win over Atlanta. They are tied with Seattle for the AL West lead and will try to take sole possession of first place with a win on Monday.

Houston averages 4.24 runs per game, which is 24th in the league. Their .252 batting average is seventh in the league. Their .318 on base percentage is 14th, as is their .400 slugging percentage.

Jeremy Pena leads Houston with a .299 batting average. Jose Altuve leads the team with 25 home runs, while Christian Walker leads the team with 80 RBI.

Houston is giving up 4.07 runs per game, which is eighth in the league. Opponents have a .231 batting average against the Astros, which is third in the league. Their 3.83 ERA is ninth, while their 1.21 WHIP is fifth.

In his last start, Alexander gave up three hits and no runs in seven innings, leading to a 3-2 win over Toronto.

Texas Rangers vs. Houston Astros Pick

Money Line Pick for Rangers vs.  Astros

  • Houston Astros ML (4 Units)

The Astros have won three of their last four games, while the Rangers split their last four road games. Houston has the edge here because they’ve had a lot of success batting against right-handers, and they’re going up against Leiter, who gave up seven runs in his last three starts. He gave up six runs in two starts against the Astros this season and will have a hard time slowing them down.

Texas won't be as successful offensively because they haven’t had as much success against right-handers, and they’re going up against Alexander, who has done a good job on the mound, giving up six runs in his last three starts. With Houston’s bullpen also playing well, they won't have trouble keeping Texas’ offense in check. Take Houston on the money line.

Over/Under Pick for Rangers vs. Astros

  • Under (4 Units)

The Astros played under the total in five of their last six games. Houston averages 4.24 runs per game and 3.93 runs per game at home. They’re batting .253 against right-handers, and they’re facing a starter who gave up seven runs in his last three starts. The Rangers average 4.30 runs per game and 4.43 runs per game on the road. They’re batting .240 against right-handers, and they’re facing a starter who gave up six runs in his last three starts. Don’t expect these teams to score enough runs to push the score over the total. The Astros and Rangers played under the total in three of their last four meetings.

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