Washington Nationals vs. Miami Marlins, Picks and Prediction, Wednesday, September 10, 2025
It’s another game in the National League East slated for Wednesday, Sept. 10. Read our Washington Nationals vs Miami Marlins prediction along with our other best MLB picks for the night. The Nationals are 60-84 this season and they are in last place in the NL East, but they have won four straight games. The Marlins are 66-79 and they sit in third place in the division. The Marlins have lost seven of their last eight games, too. Both teams are most likely to miss the playoffs this season. The Nationals will start Jake Irvin while Eury Perez gets the nod for the Marlins. The first pitch is set for 6:40 P.M. EST.
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Washington on 4-game winning streak
Washington is 60-84 overall this season. They are in last place in the National League East as they are 24.5 games back of the Phillies. They have the second-worst record in the National League, too. Washington has a 31-42 record when they have played on the road. They have won four straight games coming into Wednesday. The Nationals have also won seven of their last eight games. They are 6-5 against the Marlins this season. In their last game, they defeated Miami 7-5 on the road on Tuesday, Sept. 9.
Jake Irvin gets the start for the Nationals against the Marlins on Wednesday. The right-handed pitcher is 8-11 with a 5.71 ERA in 29 starts. Irvin threw 3.1 innings against the Cubs in latest start on Sept. 5. He allowed seven runs and five hits in an 11-5 loss. The Nationals are 13-16 when he has started this season. They are also 8-8 when he has started on the road. Irvin has a 6.19 road ERA this year.
The Nationals are hitting .245 this season, which ranks 18th in the league. They have scored the 10th fewest runs while they rank 21st in hits. Washington ranks sixth worst in home runs hit while they have also struck out the ninth fewest times. They are hitting .246 this season on the road and .244 since the All-Star break. They have a .279 batting average in 11 games against the Marlins.
Miami struggles at home continue
Miami is 66-79 overall this season. They are in third place in the National League East as they are 19 games back of the Phillies. The Marlins are 32-41 when they have played at home. The Marlins are 10 games back of the wild card spot as they are off the pace for a playoff spot. The Marlins have lost seven of their last eight games coming into Wednesday.
On Wednesday, the Marlins are set to start Eury Perez. The right-handed pitcher is 6-5 with a 4.66 ERA in 16 games pitched. Perez’s last start saw him throw four innings against the Nationals on Sept. 3. He allowed seven runs and eight hits in a 10-5 loss. The Marlins are 9-7 when Perez has pitched this season. They are just 3-3 when he has started at home with his home 2.25 ERA this year. Since the All-Star break, Perez has a 5.88 ERA this season.
Miami is hitting .250 this season which ranks 11th in the league. They have scored the 18th most runs while they rank seventh in hits. The Marlins have hit the fourth fewest home runs. They rank ninth in stolen bases while they have a .242 batting average at home. They are hitting .242 since the All-Star break and a .278 batting average against the Nationals this year.
Washington Nationals vs Miami Marlins Pick
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Earle Sports Bets | +2,298.00 |
| 2 |  Ross Benjamin | +1,840.00 |
| 3 |  Rob Vincilleti | +1,757.00 |
| 4 |  David Hess | +1,745.00 |
| 5 |  Dan Kaiser | +987.00 |
Spread Pick for Washington Nationals vs Miami Marlins
- Washington Nationals -1.5 (5 units)
The Nationals have had Miami’s number recently. They have lost five straight games against them and it will continue on Wednesday night. The Marlins are hitting just .242 at home and they are starting Eury Perez, who has an ERA of 5.88 in the second half of the season. Miami is just 3-3 when he starts at home. The Nationals are firing on all cylinders during this four-game winning streak along with winning seven of their last eight games. Washington is hitting .279 against the Marlins. They are also starting Jake Irvin, who has an ERA of 6.19 on the road. This is going to be a high-scoring game in a stadium where the Marlins have struggled this year. Miami has a 32-41 home record.
Take the Nationals to cover.
Over/Under Pick for Washington Nationals vs Miami Marlins
- Over 8.5 runs (5 units)
Both offenses are flying high at the moment. Washington is hitting .279 against the Marlins this year and they have won seven of their last eight games. The Marlins are hitting .278 against Washington and have the 11th-best ranked batting average. The two starting pitchers have struggled with Eury Perez owning a 5.88 ERA in the second half of the season. The Nationals are starting Jake Irvin with his 6.19 road ERA.
Take the over on Wednesday.
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