Prediction, Preview, and Odds
#2979 Chicago White Sox vs.
#2980 Cincinnati Reds
Wednesday, May 5, 2021 at 12:35pm EDT
Written by The Admiral

This article covers a past game!

View upcoming games.

Chicago White Sox (15-12) vs. Cincinnati Reds (13-14)

There's an exciting interleague affair when the Chicago White Sox take on the Cincinnati Reds on Wednesday. This is the second game of a two-game series between these teams. The first game was played on Tuesday, but this preview was written prior to the conclusion of that contest. Cincinnati is coming off a crazy 13-12 victory over the Chicago Cubs on Sunday. The White Sox were shut out by the Cleveland Indians on Sunday, 5-0.

Chicago is favored at -125 with the odds being set for Cincinnati at +105. The Reds defeated the White Sox the last time these teams met, that was September 20 of last year when Cincinnati was victorious, 7-3. The teams are 5-5 in the last 10 meetings against each other.

Plesac, Indians Blank White Sox

Zach Plesac tossed 5.2 innings of shutout ball as Cleveland blanked Chicago, 9-0 on Tuesday. The White Sox could muster just four hits and struck out 11 times in the game. They left nine runners on base.

Chicago is fourth in runs per game at 4.96 and is ninth in runs allowed per contest at 3.93. They are third in team batting average at .256 and 27th in home runs per game at 0.89.

Left-hander Dallas Keuchel will start for Chicago. The lefty is 1-1 with a 4.65 ERA in six starts the season. In his last start, he allowed up four runs on four hits and four walks in six innings against Cleveland. However, in his previous start, he threw six shutout innings.

José Abreu and Yermin Mercedes are tied for the team lead in homers with five. Abreu has driven in 19 runs and Adam Eaton is second with 18 RBI. Mercedes is hitting .395. Adam Engel and Eloy Jimenez will miss this game. Luis Robert is listed as questionable.

Castellanos Delivers Walk-Off Victory for Reds

Nick Castellanos drove home the winning run in the bottom of the 10th inning to give Cincinnati a 13-12 victory over the Chicago Cubs on Sunday. The Reds had 16 hits and walked five times. Castellanos had a career game, going 5-6 with four runs and four RBI, homering twice in the game. They followed that by getting shut out by the White Sox on Tuesday.

Cincinnati is first in runs scored at 5.59 but is 29th in runs allowed per game at 5.30. They are sixth in team batting average at .252 and first in home runs per game at 1.59 per contest.

Sonny Gray gets the start for Cincinnati. The right-hander is 0-2 with a 5.93 ERA in three starts. Gray allowed two runs on four hits and 5.2 innings in his last start, but was rocked by the Cardinals back on April 23, giving up five runs on six hits and 3.2 innings.

Castellanos is now hitting .330 with nine homers and 20 RBI. Both Jesse Winker and Tyler Naquin each have six homers. Winker is hitting .365 and has scored 20 runs while driving in 16. Shoga Akiyama and Aristides Aquino are both out for this contest. Jonathan India is listed as questionable.

Best Bets for this Game

Full-Game Side Bet

Insiders Status:


The pitching matchup on Tuesday was a solid one between these teams, but this contest should have a little more firepower to it. That would seem to bolster the Reds' odds, as they are the better offensive club, however, the pitching staff has been horrific for Cincinnati this season. They are scoring about 0.6 runs more per game than Chicago, but are allowing 1.3 runs more per game than the White Sox.

Cincinnati is struggling of late, losing nine of their last 13 games. Meanwhile, Chicago has won seven of their last 10 games. They have the better starter going and are performing better of late.

Prediction: Take the Chicago White Sox (-125)

Full-Game Total Pick

Insiders Status:


We may see nine total runs scored by the end of the fifth inning in this game. Chicago has gone over in four straight interleague games and has gone over in their last four games against NL Central teams. They have also gone over in five of their last six games on the road against the right-hander and have gone over in five of their last seven games on the road. Cincinnati has gone over in six of their last seven games at home and has gone over in five of their last seven interleague games. Plus, they have gone over in four of their last five games against teams with a winning record.

Combined these teams are averaging just a little over 10 runs per game while still allowing over nine runs per contest. The over seemed like the smart pick here.

Take Chicago to win, 6-4.

Prediction: Go over 9.0 (-115)

Written By Admir Aljic , "The Admiral"

You want someone to show you how to make some money, then talk to the Admiral, because he is your man. He has been handicapping for many years, so the Admiral knows a thing or two on how to beat the spread and get your pockets loaded with cash. The Admiral has brought his talents to StatSalt & Winners & Whiners and will always find the best pick for you.