Prediction, Preview, and Odds
#1961 San Diego Padres vs.
#1962 San Francisco Giants
Wednesday, September 15, 2021 at 9:45pm EDT
Written by Blake V.

There is going to be a lot on the line when San Diego faces San Francisco on Wednesday night in the third game of a four-game series. The Padres have lost their last four games heading into Tuesday’s contest, putting them outside of the playoff picture. San Francisco is red-hot, bringing an eight-game winning streak into the second game of this series—this story was published prior to Tuesday’s contest.

Padres trying to get back in playoff picture

San Diego needs to get its act together quickly before it falls out of the playoff hunt. The Padres have been in a rut for the last month, going 8-20 in their last 28 games. They are currently on a four-game losing streak after being swept by the Dodgers over the weekend. Their losing skid continued with a 9-1 loss to the Giants on Monday. San Diego is 19.5 games back of San Francisco in the National League West, but it is only a half-game back of Cincinnati for the second NL Wild Card spot. The Padres have held a playoff spot for a long time, but their losing skid has finally caught up to them.

Their offense ranks No. 18 with a team batting average of .240. Second baseman Jake Cronenworth and third baseman Manny Machado are tied for the lead in hits with 138 each. Cronenworth is on the injured list with a fractured finger. Shortstop Fernando Tatis Jr. has hit a team-best 38 home runs. San Diego will be facing a San Francisco pitching staff that is second in the majors with a team ERA of 3.26. Right-handed pitcher Joe Musgrove will start for San Diego. He allowed three runs across six innings against the Dodgers in his last outing. Musgrove allowed a season-high five walks and gave up at least three runs for the first time since Aug. 14. Musgrove has been great overall this year, posting a 2.93 ERA through 159.2 innings.

Giants continue stretching NL West lead

San Francisco is trending in the opposite direction, winning eight straight games heading into Tuesday’s contest. The Giants swept the Rockies and Cubs in consecutive road series before opening this series with a 9-1 win. They became the first team in the MLB to clinch a playoff berth with that victory. San Francisco scored five runs in the first inning to get off to a strong start and it never looked back. Its offense ranks eighth in the majors with a team batting average of .248. The Giants are 2.5 games ahead of the Dodgers at the top of the NL West.

Veteran shortstop Brandon Crawford leads the team with 124 hits, including 20 home runs. Catcher Buster Posey has 102 hits and is batting .300. Right fielder Mike Yastrzemski has 95 hits, while second baseman Wilmer Flores has added 90 base knocks. First baseman Brandon Belt has hit a team-best 24 homers. They will be facing a San Diego pitching staff that is ninth in the MLB with a team ERA of 3.86. San Francisco currently has four starting pitchers on the injured list, so it has not announced its starter for this game.

Best Bets for this Game

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Full-Game Side Bet

Insiders Status:


There are not going to be many people rushing to the window to bet on San Diego in this game, but sometimes the hardest bets to make are the best wagers. The Padres are in a losing rut, no doubt, but baseball is not as reliant upon momentum as other sports. They have a key advantage in the pitching matchup here. Musgrove has been one of the best starters in the NL all season, while the Giants are dealing with injuries to their rotation. They are going to have to use those bullpen guys in the first two games of the series, leaving them thin to cover all nine innings on Wednesday.

Prediction: San Diego +100

Full-Game Total Pick

Insiders Status:


While I do expect San Diego to score enough runs to grab a win, this should be a low-scoring affair. The Giants have been one of the best pitching staffs in the MLB all season—teams rarely put up crooked numbers against them. San Diego’s offense has been struggling lately, leaving value on the under here. Musgrove is an excellent starting arm who is going to be motivated in a high-impact game. The Giants have gone under in their last four Wednesday games, while Musgrove has gone under in his last four starts against the NL West.

Prediction: Under 8.5

Written By Blake Von Hagen , "Blake V."

Blake is a lifelong sports fan and hoops junkie. Prior to joining our team at Winners & Whiners and StatSalt, Blake worked for several newspapers and websites. He enjoys combining his beat writing expertise with the knack for finding the winning edge in a matchup. Blake is also an avid sports being expert and you would not be disappointed in following him on a daily basis. Remember, it’s a marathon, not a sprint.