Prediction, Preview, and Odds
#4909 San Francisco Giants vs.
#4910 Arizona Diamondbacks
Saturday, September 24, 2022 at 8:10pm EDT
Written by Adam Rauzino

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The San Francisco Giants (73-77, 71-79 RL, 69-73-8 O/U) take on the Arizona Diamondbacks (70-81, 87-64 RL, 67-79-5 O/U)  in the second of a three-game series on Saturday evening. The Giants send Alex Cobb to the hill. The Diamondbacks will reply with Merrill Kelly. The Diamondbacks lead the season series 8-5.

Cobb Targets Third Win of September

The Giants will give Alex Cobb the nod on Saturday. Cobb was solid in his previous start, limiting the potent Dodgers to only two runs on four hits in 5.1 innings, resulting in a no-decision in a game the Giants lost by a 4-3 score. The veteran right-hander features a stifling 1.90 ERA this month and has a 3.48 ERA and a 1.27 WHIP accompanied by a 6-6 record in 134.2 innings pitched on the season. Cobb has held Arizona to eight runs (seven earned) in 18 innings this year and stands at 1-1 with a 5.14 ERA in four career meetings spanning 21 innings against the foes.

San Francisco has been a streaky team recently. They had lost three in a row and rebounded by winning all four bouts of a four-game series at Coors Field this week. The Giants stand at 6-4 in their last ten clashes overall and are seven games below .500 on the road. 

Joey Bart is a young player that the Giants are hoping can develop into a dangerous hitter. The 25-year-old catcher has struggled recently and has 23 RBIs accompanied by a .678 OPS on the season. Bart is hitting a solid .304 with an .855 OPS against the Diamondbacks. 

The Giants are posting 4.37 runs per game, ranking them 13th overall. The pitching staff is carrying a 3.83 team ERA, placing them 10th in the big leagues. 

Kelly Looks to Avoid Third Straight Defeat

The D-Backs will have Merrill Kelly start this one. Kelly had trouble in his previous start, allowing five runs including two home runs in five innings against the Dodgers, and was charged with the loss to dip to 12-7. The veteran right-hander hasn’t been as effective in his last three starts, conceding seven home runs in that span, and features a 3.15 ERA and a 1.13 WHIP in 182.2 innings pitched on the year. Kelly has logged a stellar 1.27 ERA in four meetings against the Giants this season and is 5-3 with a 2.56 ERA in 84.1 career innings. 

Arizona thwarted a five-game slide by winning two of the last three meetings against the Dodgers this week. It’s been an encouraging season as the young core shows promise at the dish and on the mound. The Diamondbacks have lost three straight home games. 

Josh Rojas has fared well against the Giants' pitching, posting a .326 average with a strong .862 OPS. The 28-year-old third baseman is having a decent season, collecting 50 RBIs and a .723 OPS. Rojas has recorded eight RBIs on the month. 

The Diamondbacks have fared well at the plate recently and are averaging 4.37 runs, landing them 14th overall. The pitching staff has recorded a 4.25 team ERA, tabbing them 23rd.

Best Bets for this Game

Full-Game Side Bet

Insiders Status:


Alex Cobb isn’t the same pitcher when on the road, amassing a poor 5.16 ERA in his 10 road outings. Diamondbacks’ starter Merrill Kelly has completely dominated the Giants this season, limiting them to only four runs with a 2-0 record in 28.1 innings, which equates to a minuscule 1.27 ERA. 

Furthermore, the Diamondbacks have confidence after winning two of the last three games of their series against the Dodgers this week. Arizona plays tough at home where they are .500 on the season. Arizona has been successful against the Giants this season, leading the season series 8-5. 

Prediction: Arizona Diamondbacks -134

Full-Game Total Pick

Insiders Status:


I expect this one to go over. Alex Cobb has trouble against the Diamondbacks, registering a 5.14 ERA in 21 career innings against the rivals. Arizona is in a groove at the plate, scoring five or more runs in three out of their last four games entering Friday night.

In addition, while I expect Kelly to contain the Giants considering his success against them, the veteran has not been quite as sharp recently, posting a mediocre 4.32 ERA this month and has allowed seven homers in his last three outings. The over is also 4-1 in the Diamondbacks' last five home games against a team with a losing record.

Prediction: Over 7.5

Written By Adam Rauzino , "Adam Rauzino"

Adam has been a sports fanatic his entire life, closely following hockey, baseball, basketball, and football. He enjoys analyzing various stats, as well as studying Sabermetrics and analytics to take his picks to a whole new level. Adam has a passion for writing about various sports as well as personal finance and being an expert sports bettor. Prior to bringing his talents here to Winners and Whiners, Adam graduated with a diploma in business marketing and business finance. You would do yourself a huge favor by following Adam on a daily basis.