Prediction, Preview, and Odds
#4961 San Francisco Giants vs.
#4962 Arizona Diamondbacks
Sunday, September 25, 2022 at 3:40pm EDT
Written by Adam Rauzino

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The San Francisco Giants (74-78, 71-80 RL, 70-73-8 O/U) battle the Arizona Diamondbacks (71-82, 88-64 RL, 68-79-5 O/U) in the three-game series finale on Sunday afternoon. The Giants will send Jakob Junis to the hill. The Diamondbacks will reply with Drey Jameson. The Diamondbacks lead the season series 9-6. 

Giants Conclude Successful Road Trip

Jakob Junis will get the nod in the finale. Junis was clobbered last time out, squandering a whopping six runs (five earned) in 4.1 innings against the Rockies, and was able to escape with a no-decision in a game the Giants won. The veteran right-hander is having an inconsistent season, filing a 4.41 ERA and a 1.27 WHIP accompanied by a 4-6 record in 102 innings. Junis has limited Arizona to only two runs in 11 innings this season and features a 2.08 ERA in 17 career innings. 

The Giants are playing well, earning the win in five consecutive games entering Saturday after sweeping Colorado this week. It’s been a disappointing season but the pitching is in place to compete next year. The Giants are 6-4 in their last ten games overall.

Mike Yastrzemski has not been able to solve the D-Backs pitching, hitting an abysmal .108 with zero RBIs against the rivals. The 32-year-old slugger has 14 homers along with 49 RBIs and a .679 OPS on the season. Yaz has driven in four runs in his last five games. 

The Giants are averaging 4.37 runs per game, ranking them 13th overall. The pitching staff has filed a 3.88-team ERA, good for 13th in the big leagues. 

Jameson Shines in First Two Big League Outings

Drey Jameson will make his third start of the season on Sunday. Jameson has looked great in his first big league action. He tossed seven shutout innings against the Padres in his MLB debut, and followed with another strong outing, holding the Dodgers to two runs in six innings, leading to a 5-2 win. The rookie had big trouble in the Minor Leagues, recording a 6.32 ERA and a 1.49 WHIP in 132.2 innings. 

The Diamondbacks went 2-3 in a five-game road series against the Dodgers this week. They are only 3-7 in their last ten games due to a challenging schedule this month but have been competitive and usually have no issues scoring runs. 

Dalton Varsho has collected 11 RBIs and a decent .769 OPS against the Giants this season. The 26-year-old slugger is enjoying a breakout season, delivering 26 homers with 71 RBIs and a .763 OPS. Varsho has cooled recently, posting only two RBIs in his last ten games. 

Arizona is scoring an average of 4.34 runs on the year, landing them 19th overall. The pitching staff enters with a 4.25 team ERA, positioning them 24th in the Major Leagues. 

Best Bets for this Game

Full-Game Side Bet

Insiders Status:


The Giants are in a groove, winning five out of their last six games. Arizona is scuffling, dropping seven out of their last ten games. Giants’ starter Jakob Junis has contained the Diamondbacks, limiting them to only two runs in 11 innings this season, and features a stifling 2.08 career ERA gains the foes.

Furthermore, the Giants should be able to solve Drey Jameson. While the rookie has fared well in his first two career outings, he struggled in a big way in the Minor Leagues where he posted a 6.32 ERA and a 1.49 WHIP.

Prediction: San Francisco Giants +107

Full-Game Total Pick

Insiders Status:


The over is a strong play. The Giants are consistently generating offense, plating at least five runs in four out of their last five games including six in Friday's victory. They are up against a rookie pitcher and will take advantage.

In addition, the Diamondbacks should contribute to this total. Junis hasn’t been effective recently, filing a 5.95 ERA in his four starts this month. The D-Backs have averaged decent 4.30 runs against the Giants this season. The over is also 4-1 in the Diamondbacks' last five home games against a team with a losing record.

Prediction: Over 8.5

Written By Adam Rauzino , "Adam Rauzino"

Adam has been a sports fanatic his entire life, closely following hockey, baseball, basketball, and football. He enjoys analyzing various stats, as well as studying Sabermetrics and analytics to take his picks to a whole new level. Adam has a passion for writing about various sports as well as personal finance and being an expert sports bettor. Prior to bringing his talents here to Winners and Whiners, Adam graduated with a diploma in business marketing and business finance. You would do yourself a huge favor by following Adam on a daily basis.