Prediction, Preview, and Odds
#267 Los Angeles Chargers vs.
#268 Arizona Cardinals
Sunday, November 27, 2022 at 4:05pm EST
University of Phoenix Stadium, Glendale
Written by David Delano

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The Arizona Cardinals (4-7) will host the Los Angeles Chargers (5-5) on Sunday in an AFC vs. NFC West showdown. This will be only the fifth time these teams have met since 2006.

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Looking to snap losing streak

If the season ended now, the Chargers would miss the playoffs. The Chargers are currently ninth in the AFC and on a two-game losing streak after falling to the 49ers and Chiefs.

Los Angeles is sixth in the NFL passing for 263.8 yards per game but just 30th with 87.9 rushing yards per game. Justin Herbert has thrown 16 touchdowns and seven interceptions and is 12th in the NFL in QBR. Herbert is expected to have wide receiver Keenan Allen for only the fourth time this season on Sunday. Allen had eight catches for 94 yards against the Chiefs last week.

The Chargers defense is 30th allowing 148.4 rushing yards per game, and 19th giving up 220.6 passing yards. Inside the RedZone, Los Angeles is 20th scoring a touchdown on 52.8% of its trips, but sixth allowing a touchdown 51.4% of the time on defense. They are also tied for ninth in the NFL in turnover margin.

Dominated in Mexico

Arizona has dropped three of its last four games, after a 38-10 blowout loss to the 49ers last Monday. They are 12th in the NFC and have a lot of work to do to get into. They will have a bye next week and will then face the Patriots on a Monday night. The Cardinals have done a good job ranking sixth in the NFL with a +0.3 turnover differential per game.

The Cardinals' offense is 16th throwing for 223 yards per game and 21st rushing for 108.9 yards per game. After missing the last two games, Kyler Murray is expected to return on Sunday. Murray is 23rd in the NFL with a 47.0 QBR with 12 touchdowns and six interceptions. Murray has also rushed for 359 yards and two touchdowns.

The Cardinal defense has struggled in the RedZone ranking 30th allowing a touchdown 69% of the time. On offense, the Cardinals are 12th scoring a touchdown on 59.4% of their RedZone trips.

Best Bets for this Game

Full-Game Side Bet

Insiders Status:


The Chargers are still alive in the AFC wild-card race. They have dropped their last two contests, but they did show heart in those defeats covering the 8.5-point spread in their 22-16 loss to the 49ers and also covered the five-point spread in their 30-27 loss to Kansas City last week. Although not mathematically eliminated, the Cardinals' season as a legit postseason contender is over. Arizona also did not look inspired in Monday's 28-point loss to the 49ers. Now on a short week, Arizona returns to their home field where they have only covered the spread in two of their last 11 games. Los Angeles has covered the spread in five of their last six games when coming off a loss, and I expect them to get the job done on Sunday.

Prediction: Los Angeles Chargers -3

Full-Game Total Pick

Insiders Status:


The Chargers have struggled to stop the run, and the Cardinals have had issues stopping the pass this season. After playing five straight unders, Arizona has seen over cash in its last five games. The Charges have also played to the over in seven of their last eight road games against a team with a losing home record. I expect to see points in this one. I am going over with the Chargers winning 28-21.

Prediction: Over 48

Written By David Delano , "David Delano"

David Delano is a Bowling Green State University graduate with a passion for sports, traveling, and music. David loves to handicap MLB, NFL, NCAAF, NCAAB, NBA, WNBA, and is also a big fan of boxing and track and field. Over the years, David has worn several hats in the sports world, from being behind the camera to writing, filming, editing, scouting, and coaching, along with servicing his clients as a sports handicapper.  He is also an expert sports bettor. We are glad to have David on our Winners & Whiners team, and we recommend that you follow along with him every day. 

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