Prediction, Preview, and Odds
#267 Minnesota Vikings vs.
#268 San Francisco 49ers
Sunday, November 28, 2021 at 4:25pm EST
Levi's Stadium, Santa Clara
Written by Nick Raffoul

This article covers a past game!

View upcoming games.

The Minnesota Vikings will head on the road to Levi’s Stadium in Santa Clara, California on Sunday afternoon for an NFC showdown against the San Francisco 49ers.

After back-to-back wins, San Francisco finds itself with a .500 record through 10 games, good for third place in the NFC West standings. Meanwhile, the Vikings are in a similar position with a 5-5 record in 10 contests. Following consecutive victories, the Vikings find themselves back in the mix in the NFC North standings, where they trail the division-leading Green Bay Packers by just two games.

Can Minnesota take care of business against the surging 49ers on Sunday afternoon?

Griffen sent home, expected to miss game vs. 49ers

Minnesota escaped with a 34-31 win at home against the Green Bay Packers last weekend. Quarterback Kirk Cousins completed 24-of-35 passes for 341 yards with three touchdowns while Dalvin Cook added 86 rushing yards and a score for the Vikings in the win. Justin Jefferson caught eight balls for 169 yards and two touchdowns for Minnesota, which won on a 29-yard made field goal from kicker Greg Joseph as time expired.

Cousins has quietly put together the best season of his career. The 33-year-old signal-caller has completed 68.2 percent of his passes for 2,775 yards with 21 touchdowns and only two interceptions this year. In fact, Cousins hasn’t thrown an interception in five games, a span of 183 attempts.

The Vikings have placed veteran defensive end Everson Griffen on the reserve/non-football illness list two days after he refused to come out of his home and was transported to a mental health facility. Griffen, 33, refused to come out of his home following a disturbing series of posts he made on social media, including one in which he held a gun and said people were trying to kill him. Griffen was officially ruled out for Minnesota’s Week 12 contest versus the 49ers, according to ESPN.

On defense, Minnesota has given up 24.2 points per game, including 397.8 yards of total offense per contest.

49ers trounce Jags to get back to .500-mark

San Francisco thumped Jacksonville 30-10 last weekend behind another strong defensive performance. Jimmy Garoppolo passed for 176 yards and two touchdowns while wide receiver Deebo Samuel led the team in rushing with eight carries for 79 yards and a touchdown in the win.

Head coach Kyle Shanahan continues to use his receivers in the run game to keep defenses off balance. Samuel has been arguably the team’s biggest threat on the ground out wide. He’s racked up 137 yards on 19 rush attempts this season to go along with three rushing touchdowns. The third-year receiver also leads the team in receiving with 55 catches for 994 yards and five touchdowns this year.

On defense, San Francisco has surrendered 22.2 points per game, which ranks ninth in the NFL. The 49ers have also limited opponents to just 318.3 yards of total offense per contest, good for sixth in the league. Led by Nick Bosa, who has 10 sacks already this season, the 49ers rank third in the league against the pass at 202.4 total yards per game.

Best Bets for this Game

Full-Game Side Bet

Insiders Status:


Minnesota has made a habit of high-stress finishes this season. The only team in the NFL this year to own a lead of seven or more points in every game this season, Minnesota’s 5-5 record is partially a testament to its inability to close games. All but one of Minnesota's games have been decided by one score, including last week’s win over the Packers. However, the Vikings may have met their match here against a 49ers team that has excelled against the pass this year. San Francisco should also be able to move the ball on the ground in this game, which bodes well for its chances at home here. Take San Francisco to cover the spread at Levi’s Stadium on Sunday.

Prediction: San Francisco 49ers -3

Full-Game Total Pick

Insiders Status:


These two teams are projected for 49 points but that number might be hard to come by in this spot. Minnesota is due for some regression on offense after scoring 27 points or more in three consecutive weeks. Meanwhile, San Francisco has been stout on defense in recent weeks, holding the L.A. Rams and Jags to just 10 points in back-to-back contests. Look for San Francisco to try to control the clock in this game and take the under in this NFC showdown at Levi’s Stadium on Sunday.

Prediction: Under 49

Written By Nick Raffoul , "Nick Raffoul"

Shortly after graduating with an Honors in Business Administration, Nick turned his attention from traditional stocks and bonds to investing in the performance of sports teams. He has been a very successful sports bettor over the years and has now brought his talents to us here at Winners & Whiners. Nick uses a combination of advanced stats and historical data to create sports investment models to identify value and generate consistent profits. Let Nick win for you.