MLB Best Bets for Opening Day – 3 MLB Expert Picks For Today

Looking for MLB best bets? We have you covered at Winners and Whiners. Baseball is back, and while it’s not the first games of the season thanks to the Dodgers and Cubs playing last week – today is what is being celebrated as Opening Day.

Without further ado, let’s get into it, as we will detail our three best bets for Opening Day, why it makes sense, and where to find more expert picks on our platform.

Three Opening Day MLB Best Bets

• Red Sox moneyline (-112, FanDuel)
• Phillies run line (+118, BetMGM)
• Mets moneyline (+115, BetRivers)

Our three best bets are listed above, with odds from FanDuel, BetMGM, and BetRivers respectively. But remember to shop for the best MLB odds at your legal sportsbook to ensure the best price and you have a better chance of being a profitable bettor in the long run.

Expert Analysis on Today’s MLB Best Picks

At Winners and Whiners, there are dozens of expert MLB handicappers that provide expert analysis on each and every game on our MLB predictions hub. Each of these picks can be found with full analysis from our game breakdowns, to add more analysis to these picks.

• Red Sox vs Rangers
• Phillies vs Nationals
• Mets vs Astros

Crochet and the Red Sox win on Opening Day

One of the top stories in Boston this summer will be the potential breakout of ace Garrett Crochet. This is Crochet’s first year with the Red Sox, and he has been dominant in spring training. The 6’6 southpaw threw 15.2 innings and had 30 strikeouts while allowing just a single run.

In Crochet’s career, both left and right-handed hitters have a combined OPS of below .640, and he has fared better against righties allowing just a .217 batting average. This is good news for him against the Rangers, who should trot out five right-handed hitters and two switch-hitters, giving him an edge despite what looks like a negative on the surface.

Could underpriced Phillies dominate on Opening Day?

Without a doubt, the Phillies will be a popular run-line pick for today as they are +118 against one of the worst teams (projected, at least) in the National League. Despite being on the road, the Phils have their ace on the mound today and a lineup full of right-handed hitters. That bodes well against MacKenzie Gore, a southpaw for the Nationals.

The interesting part about Gore is he actually struggles more against left-handed hitters in his career (.816 OPS allowed), which is great news for big bats Kyle Schwarber and Bryce Harper, should they get to hit with runners on base. With an edge both on the mound and in the batters’ box, the Phils have a great chance to cover the run-line at plus money today.

Mets start 2025 campaign as a valuable underdog

The revamped Mets come into 2025 brimming with expectations after an unexpected run to the NLCS last year and some major offseason additions including potential MVP candidate and certified stud Juan Soto. Another one of the more intriguing additions is Clay Holmes who will toe the rubber for the Amazin’s today. Holmes was dominant in the preseason notching a dazzling 0.93 ERA over 19.1 innings.

This line appears a touch off when you factor in that the Astros offense looks poised to take step back with the departure of Alex Bregman and Kyle Tucker. While Houston appears to have a slight edge on the hill today, Holmes could easily erase that if he is able to carry over his preseason success. We will roll with a much better New York offense at a nice underdog price.

More MLB Expert Picks for Today

If you are looking for more MLB picks for today, you can find our free predictions by simply choosing the “MLB” tab in the navigation. For premium expert picks, there are dozens of handicappers offering picks for today and the entire season. Here is a look at the top MLB cappers available with their all-time MLB records.