Pro Sports Picks
Event: (117) Duke at (118) Virginia
Sport/League: CFB
Date/Time: December 6, 2025 8:00 PM EST
Free College Football Pick Today: Virginia -170
PSP Data Driven 1* Virginia.
At Professionalsportspicks we see a future where those handicapping sports without advanced analytics and data-driven strategies will be left behind. Our data-driven picks use data integration, search and discovery, and knowledge management along with collaboration with our in-house handicappers. By isolating relevant trends, removing human bias, and targeting only lines with a positive expected value above a certain threshold, our data-driven picks promise to outperform any and all human competitors.
Our models suggest that the value is on the favorite. Virginia is 9-1 SU in its last 10 games. Duke is 1-9 SU in its last 10 games against Virginia.
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Sniper Wes
Event: (107) North Texas at (108) Tulane
Sport/League: CFB
Date/Time: December 5, 2025 8:00 PM EST
Free College Football Pick Today: North Texas -125
We’ve got the AAC Championship from Yulman Stadium in New Orleans, and weather will definitely play a role. Rain is expected throughout, but with no wind, North Texas’ pass-heavy attack should still operate just fine. QB Drew Mestemaker posted a 178.2 rating, and even in wet conditions, we expect the Mean Green to move the ball through the air.
North Texas also brings balance, they’ve been one of the most productive offenses in the nation, ranking #8 with 512 yards per game. Rain or not, this team can attack multiple ways.
Tulane is tough, especially at home where they finished 6-0, but North Texas has been a betting machine all year at 10-2 ATS. There’s a reason they’re favored on the road in a conference title game.
We trust the matchup, the offense, and the number.
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Event: (105) Troy at (106) James Madison
Sport/League: CFB
Date/Time: December 5, 2025 7:00 PM EST
Free College Football Pick Today: James Madison -23.0 (-109)
We get 8-4 Troy vs 11-1 James Madison. Both these teams are 8-4 ATS as well which is really impressive on the Dukes side, as they are always favored and sometimes favored heavily, and they continue to cover the number. These teams have played once before in 2023, and JMU won 16-14, and obviously that was a much different Dukes team. The Trojans however are no pushover, and in a Championship Game like this, it's a lot of points.
Keep in mind however, James Madison coach Bob Chesney is headed to take the UCLA job after this season, so this could be his last time coaching this team, and we think they are up for Troy, and will want to make a big statement as they have an outside shot at getting into the final bracket with some help.
Also keep in mind the temperature will be very cold in Harrisonburg, Virginia. Troy is from Alabama, and they might even see some snow in this game, so this favors JMU as well, and we will roll with the Dukes to roll over the Trojans.
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Jesse Schule
Event: (109) UNLV at (110) Boise State
Sport/League: CFB
Date/Time: December 5, 2025 8:00 PM EST
Free College Football Pick Today: Boise State -3.5 (-120)
This is a free play on BSU.
The Broncos own the Rebels! They beat them by 25 during the regular season, and this is a rematch of last year's conference championship game where Boise State won 21-7. The Rebels sit on 10 wins while Boise is just 8-4, but it's important to weigh strength of schedule. The Rebels only win against a team with a winning record came at home against Hawaii. Yes the Broncos lost starting QB Maddux Madsen, but the backup has settled in after a handful of starts, and the lit up the Aggies on the road in a win at Utah State last week. I like Boise to win this game by double digits.
GL,
Jesse Schule
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Event: (103) Kennesaw State at (104) Jacksonville State
Sport/League: CFB
Date/Time: December 5, 2025 7:00 PM EST
Free College Football Pick Today: Kennesaw State -2.5 (-109)
We get 9-3 Kennesaw State vs 8-4 Jacksonville State in the Conference USA Championship in Jacksonville Alabama. The line opened as the Gamecocks a -1.5 favorite, only to have the line flip to the Owls now being favored. Jacksonville State won the head to head meeting back on November 15th, and we think Kennesaw State will play much better this time as they have seen the Gamecocks run game already, and the Owls were 7-4-1 ATS on the season, so we think they do quite well here and cover this short number as a road favorite, and with Conference USA.
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Joe Duffy
Event: (119) Indiana at (120) Ohio State
Sport/League: CFB
Date/Time: December 6, 2025 8:00 PM EST
Free College Football Pick Today: Indiana +5.0 (-109)
Indiana-Ohio State
Opener: Ohio State -5.5, 48.5
Best lines: Ohio State -4.5 -110, Indiana +5.5 +110
Best totals: OVER 48.5 -102, UNDER 48.5 -109
Splits on side: 58% of bets, 88% of cash on Indiana
Splits on total: 76% of bets, 77% of cash on over
- At Lucas Oil Stadium, so hardly neutral
- Ohio State is about 178 miles
- Indiana 50
- Indiana is 7-5 ATS but by a nation’s best 11.6 margin of cover
- Ohio 10-1-1 but by only 6.3 points per game
- Ohio State under 8-4 by -4 points per game
- Indiana over 7-5 +3.6 points per game
- Public starts to like dogs in postseason and/or ranked dogs
- Teams off a road win in a game in which they attempted 10 or fewer first downs is 215-138-8 (Indiana)
- Undefeated underdogs of 2.5 or more in game 6 or later are 139-112-7 (Indiana)
- Go with favorite of 3 or more in battle of two ranked teams if not playing a true road game is 399-291-18 (Ohio State)
- SportsLine has Ohio State winning 27-22
- Teams off dominant rushing games (at least 300 yards plus other factors) go under 585-396-25
- Neutral games are not home or away
- Ohio State 18-2 ATS with no more than six days rest after completing 19 or fewer passes last game
- Indiana QB Fernado Mendoza vs. Ohio State Julian Sayin Heisman battle
- If it’s possible for a team to get a letdown in a conference championship game, it’s here
- Ohio State finally snapped Michigan’s 4-game winning streak
- Defending national champs, looking at bigger picture
- Indiana only second year as powerhouse and has doubters
Free pick from Joe Duffy’s Picks: INDIANA +5 as tough for Ohio State to avoid true sandwich game in Big 10 championship
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